<?xml version='1.0' encoding='UTF-8'?><?xml-stylesheet href="http://www.blogger.com/styles/atom.css" type="text/css"?><feed xmlns='http://www.w3.org/2005/Atom' xmlns:openSearch='http://a9.com/-/spec/opensearchrss/1.0/' xmlns:georss='http://www.georss.org/georss' xmlns:gd='http://schemas.google.com/g/2005' xmlns:thr='http://purl.org/syndication/thread/1.0'><id>tag:blogger.com,1999:blog-8977896270362279183</id><updated>2011-04-21T11:39:24.714-07:00</updated><category term='video'/><category term='definition'/><title type='text'>Insomnia Therapy Center</title><subtitle type='html'>The Information Center about Insomnia and Sleep disorder and also the tips for against both.</subtitle><link rel='http://schemas.google.com/g/2005#feed' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/posts/default'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default?max-results=100'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/'/><link rel='hub' href='http://pubsubhubbub.appspot.com/'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><generator version='7.00' uri='http://www.blogger.com'>Blogger</generator><openSearch:totalResults>5</openSearch:totalResults><openSearch:startIndex>1</openSearch:startIndex><openSearch:itemsPerPage>100</openSearch:itemsPerPage><entry><id>tag:blogger.com,1999:blog-8977896270362279183.post-6588040046368014707</id><published>2009-04-28T04:29:00.000-07:00</published><updated>2009-04-28T04:36:43.738-07:00</updated><category scheme='http://www.blogger.com/atom/ns#' term='video'/><title type='text'>sleep disorder video on youtube.com</title><content type='html'>&lt;span style="font-weight:bold;"&gt;sleep disorder video on youtube.com&lt;/span&gt;&lt;br /&gt;&lt;object width="406" height="252"&gt;&lt;param name="movie" value="http://www.youtube-nocookie.com/v/6JU4uGcMm6I&amp;hl=en&amp;fs=1&amp;border=1"&gt;&lt;/param&gt;&lt;param name="allowFullScreen" value="true"&gt;&lt;/param&gt;&lt;param name="allowscriptaccess" value="always"&gt;&lt;/param&gt;&lt;embed src="http://www.youtube-nocookie.com/v/6JU4uGcMm6I&amp;hl=en&amp;fs=1&amp;border=1" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="406" height="252"&gt;&lt;/embed&gt;&lt;/object&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/8977896270362279183-6588040046368014707?l=insomniatherapycenter.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/6588040046368014707/comments/default' title='Poskan Komentar'/><link rel='replies' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/sleep-disorder-video-on-youtubecom.html#comment-form' title='0 Komentar'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/6588040046368014707'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/6588040046368014707'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/sleep-disorder-video-on-youtubecom.html' title='sleep disorder video on youtube.com'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><thr:total>0</thr:total></entry><entry><id>tag:blogger.com,1999:blog-8977896270362279183.post-5637621925649200802</id><published>2009-04-28T03:38:00.000-07:00</published><updated>2009-04-28T03:51:08.908-07:00</updated><category scheme='http://www.blogger.com/atom/ns#' term='definition'/><title type='text'>Sleep Terms, Definitions and Abbreviations</title><content type='html'>&lt;div align="center"&gt;&lt;b&gt;&lt;font color="#663333" face="Arial, Helvetica, sans-serif"&gt;Definitions&lt;/font&gt;&lt;/b&gt;&lt;font face="Arial, Helvetica, sans-serif"&gt; &lt;br /&gt;    choose first letter&lt;/font&gt; &lt;br&gt;&lt;br /&gt;  &lt;/div&gt;&lt;br /&gt;          &lt;p align="center"&gt;&lt;a href="#A"&gt; A&lt;/a&gt; &lt;a href="#B"&gt;B&lt;/a&gt; &lt;a href="#C"&gt;C&lt;/a&gt; &lt;br /&gt;    &lt;a href="#D"&gt;D&lt;/a&gt; &lt;a href="#E"&gt;E&lt;/a&gt; &lt;a href="#F"&gt;F&lt;/a&gt; &lt;a href="#G"&gt;G&lt;/a&gt; &lt;br /&gt;    &lt;a href="#H"&gt;H&lt;/a&gt; &lt;a href="#I"&gt;I&lt;/a&gt; &lt;a href="#J"&gt;J&lt;/a&gt; &lt;a href="#K"&gt;K&lt;/a&gt; &lt;br /&gt;    &lt;a href="#L"&gt;L&lt;/a&gt; &lt;a href="#M"&gt;M&lt;/a&gt; &lt;a href="#N"&gt;N&lt;/a&gt; &lt;a href="#O"&gt;O&lt;/a&gt; &lt;br /&gt;    &lt;a href="#P"&gt;P&lt;/a&gt; &lt;a href="#Q"&gt;Q&lt;/a&gt; &lt;a href="#R"&gt;R&lt;/a&gt; &lt;a href="#S"&gt;S&lt;/a&gt; &lt;br /&gt;    &lt;a href="#T"&gt;T&lt;/a&gt; &lt;a href="#U"&gt;U&lt;/a&gt; V &lt;a href="#W"&gt;W&lt;/a&gt; X Y &lt;a href="#Z"&gt;Z &lt;br /&gt;    &lt;/a&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;h4 align="center"&gt;&lt;font face="Arial, Helvetica, sans-serif" color="#990099"&gt;&lt;a href="#ABB"&gt;Abbreviations&lt;/a&gt; &lt;br /&gt;    &lt;font color="#663333"&gt;click to jump&lt;/font&gt;&lt;/font&gt;&lt;br&gt;&lt;br /&gt;  &lt;/h4&gt;&lt;br /&gt;&lt;p&gt;&lt;font face="Arial" size="2"&gt;&lt;b&gt;&lt;font size="-1"&gt;Abdominal &lt;br /&gt;      Movement&lt;/font&gt;&lt;/b&gt;&lt;font size="-1"&gt;&lt;a name="A"&gt;&lt;/a&gt; - In diagnostic sleep studies, abdominal movement &lt;br /&gt;      is recorded. This is one of the measures of respiratory effort, reflecting &lt;br /&gt;      movement of the diaphragm.  &lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Advanced Sleep Phase Syndrome&lt;/b&gt; &lt;b&gt;(ASPS)&lt;/b&gt; &lt;br /&gt;      - Phases of the daily sleep/wake cycle are advanced with respect to clock &lt;br /&gt;      time.  This is classified as a circadian rhythm disorder.   The sleep phase &lt;br /&gt;      occurs well ahead of the conventional bedtime and the tendency is to wake &lt;br /&gt;      up too early. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Alpha &lt;br /&gt;      rhythm&lt;/b&gt; - EEG oscillations, prominent over the occipital cortex, with &lt;br /&gt;      a frequency of 8-13 Hz in adults;  indicative &lt;br /&gt;      of the awake state; present in most, but not all, normal individuals;  &lt;br /&gt;      most consistent and predominant during relaxed wakefulness. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Alpha &lt;br /&gt;      intrusion&lt;/b&gt; - brief occurrence of alpha activity during a stage of sleep. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Ambulatory &lt;br /&gt;      Monitor&lt;/b&gt; - Portable system used to record (continuously) multiple physiological &lt;br /&gt;      variables during sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;br /&gt;          &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Apnea&lt;/b&gt; &lt;br /&gt;      - Literally means &amp;quot;no breath&amp;quot;;  &lt;br /&gt;      the cessation of airflow at the nostrils and mouth for at least 10 &lt;br /&gt;      seconds.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Apnea &lt;br /&gt;      index (AI)&lt;/b&gt; - A measure of the severity of sleep apnea;  the number of apnea events per hour.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Apnea/Hypopnea &lt;br /&gt;      index (AHI)&lt;/b&gt; - the number of apneas and hypopneas per hour. 5-20=mild, &lt;br /&gt;      21-50=moderate, above 51 severe  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Arousal&lt;/b&gt; &lt;br /&gt;      - abrupt change from sleep to wakefulness, or from a &amp;quot;deeper&amp;quot; &lt;br /&gt;      stage of non-REM sleep to a &amp;quot;lighter&amp;quot; stage &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Arousal &lt;br /&gt;      Disorder&lt;/b&gt; - parasomnia disorder presumed to be due to an abnormal arousal &lt;br /&gt;      function.  Classical arousal disorders:  &lt;br /&gt;      sleepwalking, sleep terrors and confusional arousals. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Arousal &lt;br /&gt;      Threshold&lt;/b&gt; - ease that a sleeping person is awakened. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Arrhythmia&lt;/b&gt; &lt;br /&gt;      - irregularity or absence of the heart rhythm caused by disturbances in &lt;br /&gt;      transmission of electrical impulses through cardiac tissue. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Auto Adjusting Continuous Positive Airway &lt;br /&gt;      Pressure Device (SmartPAP) (Auto-PAP)&lt;/b&gt; - A type of CPAP machine monitoring &lt;br /&gt;      changes in breathing and compensates automatically by making appropriate &lt;br /&gt;      adjustments in pressure. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Automatism&lt;/b&gt; &lt;br /&gt;      - automatic action--especially any action performed apparently without intention &lt;br /&gt;      or awareness. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Basic &lt;br /&gt;      Sleep Cycle&lt;a name="b"&gt;&lt;/a&gt;&lt;/b&gt; - progression through orderly succession &lt;br /&gt;      of sleep states and stages. For the healthy adult, the first cycle is begins &lt;br /&gt;      by going from wakefulness to non-REM sleep. The first REM period follows &lt;br /&gt;      the first period of non-REM sleep, and the two sleep states continue to &lt;br /&gt;      alternate throughout the night with an average period of about 90 minutes. &lt;br /&gt;      A night of normal human sleep usually consists of 4-6 non-REM/REM sleep &lt;br /&gt;      cycles. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Benzodiazepines&lt;/b&gt; - developed in the 1950's, &lt;br /&gt;      this class of compounds tranquilize and sedates. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Beta &lt;br /&gt;      Activity&lt;/b&gt; - brain waves with a frequency of greater than 13 Hz (Hertz). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Bi-Level&lt;/b&gt; - Bi-level pressure device &lt;br /&gt;      used to treat sleep apnea.  The &amp;quot;bi&amp;quot; refers to two pressures:  &lt;br /&gt;      a lower pressure for exhalation and a higher pressure for inhalation.  Bi-Level &lt;br /&gt;      machines are more expensive than a standard CPAP, but some patients tolerate &lt;br /&gt;      it better because they can exhale comfortably against the constant inhalation &lt;br /&gt;      pressure. (Sometimes called &lt;b&gt;Bi-PAP, &lt;/b&gt;but that is a trademark name &lt;br /&gt;      of one system)&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Biological &lt;br /&gt;      Clock&lt;/b&gt; - term for the brain process causing us to have 24-hour fluctuations &lt;br /&gt;      in body temperature, hormone secretion, and other bodily activities. The &lt;br /&gt;      most important function fosters the daily alternation of sleep and wakefulness. &lt;br /&gt;      The biological clock is found in a pair of tiny bilateral brain areas called &lt;br /&gt;      the suprachiasmatic nuclei. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Body &lt;br /&gt;      Position&lt;/b&gt; - four positions are identified which a patient may be sleeping; &lt;br /&gt;      back, left side, right side or abdomen. The time spent sleeping in each &lt;br /&gt;      position and the number of respiratory events in a particular position are &lt;br /&gt;      tabulated.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Bradycardia&lt;/b&gt; &lt;br /&gt;      - heart rhythm with a rate lower than 60 beats per minute in an adult. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Brain &lt;br /&gt;      Waves&lt;/b&gt; – the brain’s spontaneous electrical activity studied by electroencephalography &lt;br /&gt;      (EEG). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Bruxism&lt;/b&gt; &lt;br /&gt;      – teeth grinding during sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Cardiac &lt;br /&gt;      Arrest&lt;a name="C"&gt;&lt;/a&gt;&lt;/b&gt; - sudden cessation of the heart beat. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Cardiovascular&lt;/b&gt; &lt;br /&gt;      - Pertaining to blood vessels  and &lt;br /&gt;      the heart  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Cataplexy&lt;/b&gt; &lt;br /&gt;      - sudden, dramatic decrement in muscle tone and loss of deep reflexes that &lt;br /&gt;      leads to muscle weakness, paralysis, or postural collapse.  Usually caused by outburst of emotion:  laughter, startle, or sudden physical exercise; &lt;br /&gt;      one of the tetrad of symptoms of narcolepsy.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Central &lt;br /&gt;      apnea&lt;/b&gt; - absence of airflow and inspiratory effort;  apnea caused by irregularity in the brain's control of breathing. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Central &lt;br /&gt;      Nervous System (CNS)&lt;/b&gt; - brain and spinal cord. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Cheyne-Stokes &lt;br /&gt;      respiration&lt;/b&gt; - breathing pattern typified by regular &amp;quot;crescendo-decrescendo&amp;quot; &lt;br /&gt;      or waxing and waning fluctuations in respiratory rate and tidal volume. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Chronotherapy&lt;/b&gt; &lt;br /&gt;      - treatment for circadian rhythm sleep disorder by systemically changing &lt;br /&gt;      sleeping and waking times to reset the biological clock. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Circadian rhythm&lt;/b&gt; - innate, daily, fluctuation &lt;br /&gt;      of behavioral and physiological functions, including sleep waking, generally &lt;br /&gt;      tied to the 24 hour day-night cycle but sometimes to a different (e.g., &lt;br /&gt;      23 or 25 hour) periodicity when light/dark and other time cues are removed.  &lt;br /&gt;      &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Compliance&lt;/b&gt; &lt;br /&gt;      - adhering to or conforming with a regimen of treatment such as CPAP &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;CPAP &lt;br /&gt;      - Continuous Positive Airway Pressure&lt;/b&gt;;  &lt;br /&gt;      the device used to treat sleep apnea by sending positive airway pressure &lt;br /&gt;      at a constant, continuous pressure to help keep an open airway, allowing &lt;br /&gt;      the patient to breathe normally through his/her nose and airway &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;CPAP &lt;br /&gt;      Pressure&lt;/b&gt; - pressure needed to maintain an open airway in a sleep apnea &lt;br /&gt;      patient treated with CPAP, expressed in centimeters of water (cm H20). The &lt;br /&gt;      positive pressure can range from 5 - 20 cm H20. Different patients require &lt;br /&gt;      different pressures. The value is determined in a CPAP titration study. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Deep &lt;br /&gt;      Sleep&lt;a name="D"&gt;&lt;/a&gt;&lt;/b&gt; - refers to combined non-REM sleep stages 3 and &lt;br /&gt;      4 in sleep studies &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Delayed &lt;br /&gt;      sleep phase&lt;/b&gt; - A condition occurring when the clock hour at which sleep &lt;br /&gt;      normally occurs is moved back in time in a given, 24 hour sleep-wake cycle. &lt;br /&gt;      The result is a temporarily displaced (delayed) occurrence of sleep within &lt;br /&gt;      the 24 hour cycle.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Delta &lt;br /&gt;      sleep&lt;/b&gt; - stage(s) of sleep in which EEG delta waves are prevalent or &lt;br /&gt;      predominant (sleep stages 3 and 4, respectively).  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Delta &lt;br /&gt;      waves&lt;/b&gt; - EEG activity with a frequency less than 4 Hz.  In human sleep stage scoring, conventionally the minimum criteria &lt;br /&gt;      for scoring delta waves is 75 uV (peak-to-peak) amplitude, and 0.5 second &lt;br /&gt;      duration (2 Hz).  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Diagnostic &lt;br /&gt;      Sleep Study&lt;/b&gt; - monitoring of several physiological activities in a sleeping &lt;br /&gt;      individual. Usually performed to determine the absence or presence of a &lt;br /&gt;      specific sleep disorder. The sleep study can occur in a sleep disorders &lt;br /&gt;      center or in a patient's home with portable recording equipment. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Diaphragm&lt;/b&gt; &lt;br /&gt;      - large, concave muscle attached to the rib cage at bottom of the chest &lt;br /&gt;      (top of the abdomen). Inhalation occurs when diaphragm contracts. Exhalation &lt;br /&gt;      is passive as the muscle relaxes. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Diurna&lt;/b&gt;l &lt;br /&gt;      - active and wakeful in the daytime versus active in the nighttime &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;DME - Durable Medical Equipment. Equipment&lt;/b&gt; &lt;br /&gt;      such as wheelchairs and walkers which are prescribed for use by or on the &lt;br /&gt;      order of a physician, also includes CPAP and BI-Level machines. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Drowsiness&lt;/b&gt;, &lt;br /&gt;      Drowsy - quiet wakefulness occurring prior to sleep onset.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Dyssomnia&lt;/b&gt; &lt;br /&gt;      - a disorder of sleep or wakefulness; not a parasomnia &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Electrocardiography&lt;a name="E"&gt;&lt;/a&gt; &lt;br /&gt;      (EKG)&lt;/b&gt; – a method of measuring the electrical activity of the heart. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Electrodes&lt;/b&gt; &lt;br /&gt;      - small devices transmitting biological electrical activity from subject &lt;br /&gt;      to polygraph  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Electroencephalogram &lt;br /&gt;      (EEG)&lt;/b&gt; - recording through the scalp of electrical potentials from the &lt;br /&gt;      brain and the changes in these potentials. The EEG is one of the three basic &lt;br /&gt;      variables (along with the EOG &amp;amp; EMG) used to score sleep stages and &lt;br /&gt;      waking. Surface electrodes are used to record sleep in humans, recording &lt;br /&gt;      potential differences between brain regions and a neutral reference point, &lt;br /&gt;      or between brain regions.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Electromyogram &lt;br /&gt;      (EMG)&lt;/b&gt; - recording of electrical activity from the muscular system; in &lt;br /&gt;      sleep recording, synonymous with resting muscle activity or potential. The &lt;br /&gt;      chin EMG, along with EEG and EOG, is one of the three basic variables used &lt;br /&gt;      to score sleep stages and waking. Surface electrodes are used to record &lt;br /&gt;      sleep in humans, measuring activity from the submental or masseter muscles. &lt;br /&gt;      These reflect the changes in resting muscle activity.  &lt;br /&gt;      During REM sleep the chin/cheek EMG is tonically inhibited.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Electro-oculogram &lt;br /&gt;      (EOG)&lt;/b&gt; - recording of voltage changes resulting from shifts in position &lt;br /&gt;      of the eyeball-possible because each globe is a positive (anterior) and &lt;br /&gt;      negative (posterior) dipole; along with the EEG and the EMG, one of the &lt;br /&gt;      three basic variables used to score sleep stages and waking. Human sleep &lt;br /&gt;      recordings utilize surface electrodes placed near the eyes to record the &lt;br /&gt;      movement of the eyeballs. Rapid eye movements in sleep indicate a certain &lt;br /&gt;      stage of sleep ( usually REM sleep).  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;ENT &lt;br /&gt;      &lt;/b&gt;- Ear, Nose and Throat.  A doctor &lt;br /&gt;      specializing in diseases of the Ear, Nose and Throat.  These specialists often do surgery as well, and may be referred &lt;br /&gt;      to as an ENT surgeon. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;EPAP&lt;/b&gt; &lt;br /&gt;      - Expiratory Positive Airway Pressure. Pressure prescribed for the expiratory &lt;br /&gt;      (breathing out) phase of an individual on Bi-level CPAP therapy for OSA &lt;br /&gt;      (obstructive sleep apnea). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Epidemiology&lt;/b&gt; &lt;br /&gt;      - Scientific discipline studying the incidence, distribution, and control &lt;br /&gt;      of disease in a population. Includes the study of factors affecting the &lt;br /&gt;      progress of an illness, and, in the case of many chronic diseases, their &lt;br /&gt;      natural history. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Epoch &lt;br /&gt;      &lt;/b&gt;- A standard 30 second duration of the sleep recording that is assigned &lt;br /&gt;      a sleep stage designation; for special purposes, occasionally longer or &lt;br /&gt;      shorter epochs are scored. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Epworth &lt;br /&gt;      Sleepiness Scale&lt;/b&gt; - index of sleep propensity during the day as perceived &lt;br /&gt;      by patients, and derived from the answers to 8 questions. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Esophageal &lt;br /&gt;      Pressure&lt;/b&gt; - measurement used to determine respiratory effort and by inference, &lt;br /&gt;      airway resistance. Considered an invasive measure, generally used only in &lt;br /&gt;      polysomnographic testing, conducted in sleep disorders centers. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Excessive &lt;br /&gt;      daytime sleepiness or somnolence (EDS)&lt;/b&gt; -  &lt;br /&gt;      subjective report of difficulty in staying awake, accompanied by &lt;br /&gt;      a ready entrance into sleep when the individual is sedentary &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Expiratory &lt;br /&gt;      Phase&lt;/b&gt; - air is expelled during this phase of the breathing cycle &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Fatigue&lt;a name="F"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - feeling of tiredness or weariness usually associated with performance &lt;br /&gt;      decrements &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Fiberoptic Nasopharyngoscope&lt;/b&gt; - flexible &lt;br /&gt;      fiberoptic scope used in the examination of nasal passages, pharynx, hypopharynx &lt;br /&gt;      and larynx.&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Fibromyalgia&lt;/b&gt; - a disease syndrome whose &lt;br /&gt;      primary symptoms are muscle pain and fatigue.&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Flattening &lt;br /&gt;      Index&lt;/b&gt; - number indicating the amount of airflow limitation caused by &lt;br /&gt;      partial closure of the upper airway. 0.3 indicates an open airway, 0.15 &lt;br /&gt;      is mildly obstructed, 0.1 is severely limited airflow, and 0.0 reflects &lt;br /&gt;      a totally closed airway.  Flattening &lt;br /&gt;      Index is used to identify the condition known as Upper Airway Resistance &lt;br /&gt;      Syndrome (UARS), and is continuously recorded in both diagnostic sleep studies &lt;br /&gt;      and CPAP titrations. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Flow &lt;br /&gt;      Limitation&lt;/b&gt; – the partial closure of the upper airway impeding the flow &lt;br /&gt;      of air into the lungs. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Forbidden &lt;br /&gt;      Zone&lt;/b&gt; – the period of strongest clock-dependent alerting, usually in &lt;br /&gt;      the evening. Prevents falling asleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Fragmentation (pertaining to Sleep Architecture&lt;/b&gt;) &lt;br /&gt;      - interruption of a sleep stage as a result of the appearance of a lighter &lt;br /&gt;      stage, or to the occurrence of wakefulness, which leads to disrupted non-REM-REM &lt;br /&gt;      sleep cycles. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;GABA&lt;a name="G"&gt;&lt;/a&gt; &lt;br /&gt;      (Gamma-Amniobutyric Acid&lt;/b&gt;) - major neurotransmitter in the brain, which &lt;br /&gt;      is considered to be involved in muscle relaxation, sleep, diminished emotional &lt;br /&gt;      reaction and sedation. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Gastroesphageal &lt;br /&gt;      Reflux Disease (GERD)&lt;/b&gt; - flow of stomach acid upwards into the esophagus &lt;br /&gt;      that can cause arousals and disrupt sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Genioglossus &lt;br /&gt;      tongue advancement&lt;/b&gt; – a possible surgical treatment used for sleep apnea &lt;br /&gt;      and/or snoring, improving the airway behind the base of the tongue. The &lt;br /&gt;      genioglossus, the main tongue muscle, relaxes during sleep, often allowing &lt;br /&gt;      the tongue to fall into the airway. The muscle attaches to the middle of &lt;br /&gt;      the lower jaw.  A segment of bone containing this muscle is &lt;br /&gt;      pulled forward and stabilized, opening the airway space behind the tongue.   &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Habitual &lt;br /&gt;      Snorers&lt;a name="H"&gt;&lt;/a&gt;&lt;/b&gt; - those who snore nearly every night &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Heart &lt;br /&gt;      Rate or beats per minute (bpm)&lt;/b&gt; – pace/speed of the heart measured in &lt;br /&gt;      beats per minute. 60-80 is considered normal in adults.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hertz &lt;br /&gt;      (Hz)&lt;/b&gt; - unit of frequency; equal to cycles per second (cps).  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Histogram &lt;br /&gt;      (sleep) &lt;/b&gt; - graph indicating sleep stages thoughout the night. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Humidification&lt;/b&gt; &lt;br /&gt;      - moisture is added to the airflow as an adjunct to CPAP (Continuous Positive &lt;br /&gt;      Airway Pressure) therapy in treating obstructive sleep apnea (OSA). Humidification &lt;br /&gt;      can be added to the CPAP by diverting the airflow over or through a cool &lt;br /&gt;      or heated water reservoir (humidifier) to prevent the upper airway from &lt;br /&gt;      drying out. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hyoid Suspension&lt;/b&gt; – a possible surgical &lt;br /&gt;      procedure sometimes used in the treatment of sleep apnea and/or snoring, &lt;br /&gt;      designed to improve the airway behind the base of the tongue. The hyoid &lt;br /&gt;      bone is located in the neck where some tongue muscles attach. The hyoid &lt;br /&gt;      bone is pulled forward in front of the voice box and can open the airway &lt;br /&gt;      space behind the tongue.&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hyperactivity&lt;/b&gt; – typical behavior in &lt;br /&gt;      a child with a sleep disorder which is causing lack of quality sleep&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypercapnia&lt;/b&gt; &lt;br /&gt;      – excessive or elevated carbon dioxide in the blood  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hyperirritability&lt;/b&gt; &lt;br /&gt;      - Extreme irritability; seen in sleep deprived subjects. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypersomnia&lt;/b&gt; &lt;br /&gt;      – excessive, prolonged sleep  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypertension&lt;/b&gt; &lt;br /&gt;      -High blood pressure. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypnagogic &lt;br /&gt;      imagery (-hallucinations)&lt;/b&gt; - Vivid sensory images occurring at sleep &lt;br /&gt;      onset but particularly vivid with sleep-onset REM periods;  feature of narcoleptic REM naps.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypnagogic &lt;br /&gt;      startle&lt;/b&gt; - &amp;quot;sleep start&amp;quot; or sudden body jerk, observed normally &lt;br /&gt;      just at sleep onset, resulting in at least momentary awakening &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypnophobia&lt;/b&gt; &lt;br /&gt;      - Morbid fear of falling asleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypnotics&lt;/b&gt; &lt;br /&gt;      - Sleep-inducing drugs. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypopharynx&lt;/b&gt; &lt;br /&gt;      - lowermost portion of the pharynx leading to the larynx and esophagus. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypopnea&lt;/b&gt; &lt;br /&gt;      - shallow breathing in which the air flow in and out of the airway is less &lt;br /&gt;      than half of normal--usually associated with oxygen desaturation.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypoventilation&lt;/b&gt; &lt;br /&gt;      - reduced rate and depth of breathing. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypoxemia&lt;/b&gt; &lt;br /&gt;      - abnormal lack of oxygen in the blood in the arteries.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Hypoxia&lt;/b&gt; &lt;br /&gt;      - deficiency of oxygen reaching the tissues of the body. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Imidazopyridines&lt;/b&gt;&lt;a name="I"&gt;&lt;/a&gt; &lt;br /&gt;      - New class of compounds inducing sleepiness. (Zolpidem, trade name Ambien, &lt;br /&gt;      is in this class). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Inappropriate &lt;br /&gt;      Sleep Episodes&lt;/b&gt; – unplanned sleep periods often occuring in an unsafe &lt;br /&gt;      situation (i.e., while driving). These episodes are always due to sleep &lt;br /&gt;      deprivation. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Insomnia&lt;/b&gt; &lt;br /&gt;      – complaint describing difficulty in sleeping &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Inspiratory &lt;br /&gt;      Phase&lt;/b&gt; - part of the breathing cycle in which air is inhaled. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Invasive&lt;/b&gt; &lt;br /&gt;      – referring to a medical procedure in which a bodily orifice or the skin &lt;br /&gt;      must be penetrated for the purpose of collecting data, or for diagnosing &lt;br /&gt;      or treating a disorder &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;IPAP&lt;/b&gt; &lt;br /&gt;      - Inspiratory Positive Airway Pressure.  &lt;br /&gt;      Physician prescribed pressure for the inspiratory phase on a Bi-level &lt;br /&gt;      CPAP device, used in the treatment of OSA. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Jet &lt;br /&gt;      Lag&lt;a name="J"&gt;&lt;/a&gt;&lt;/b&gt; - disturbance induced by a major rapid shift in &lt;br /&gt;      environmental time during travel to a new time zone &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;K-Alpha&lt;a name="K"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - type of microarousal;  K complex &lt;br /&gt;      followed by several seconds of alpha rhythm. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;K &lt;br /&gt;      complex&lt;/b&gt; - sharp, negative, high-voltage EEG wave, followed by a slower, &lt;br /&gt;      positive component. K complex, occurring spontaneously during NREM sleep, &lt;br /&gt;      beginning in (and defining) stage 2.  K &lt;br /&gt;      complexes can be elicited during sleep by external (particularly auditory) &lt;br /&gt;      stimuli as well.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Laser &lt;br /&gt;      assisted uvulopalatoplasty&lt;a name="L"&gt;&lt;/a&gt; (LAUP)&lt;/b&gt; - can eliminate or &lt;br /&gt;      decrease snoring but has not been shown to be effective in the treatment &lt;br /&gt;      of sleep apnea.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Leg &lt;br /&gt;      Movement &lt;/b&gt;- Leg movements are recorded in both diagnostic sleep studies &lt;br /&gt;      and titration studies.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Letter &lt;br /&gt;      of Medical Necessity (LMN)&lt;/b&gt; - certification by a physician that the prescribed &lt;br /&gt;      item(s) is/are medically indicated, reasonable and necessary with reference &lt;br /&gt;      to the standards of medical practice and treatment of a patient's condition &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Light-Dark &lt;br /&gt;      Cycle&lt;/b&gt; - periodic pattern of light (artificial or natural) alternating &lt;br /&gt;      with darkness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Light &lt;br /&gt;      Sleep&lt;/b&gt; - term used to describe non-REM sleep stage 1, and sometimes, &lt;br /&gt;      stage 2. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Light &lt;br /&gt;      Therapy&lt;/b&gt; - used in the treatment of SAD (Seasonal Affective Disorder) &lt;br /&gt;      and other conditions. Exposes the eyes to light of appropriate intensity &lt;br /&gt;      and duration and at the appropriate time of day to effect the timing, duration &lt;br /&gt;      and quality of sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Limit-Setting &lt;br /&gt;      Sleep Disorder &lt;/b&gt;– disorder due to child’s difficulty in falling asleep &lt;br /&gt;      by delaying and refusing to go to bed &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Linear &lt;br /&gt;      Sleepiness Rating Scale&lt;/b&gt; - measure of subjective sleepiness.  The scale contains a horizontal line, 100 mm &lt;br /&gt;      in length --the right extreme is labeled &amp;quot;Very Sleepy&amp;quot; and the &lt;br /&gt;      left extreme is labeled &amp;quot;Very Wide Awake.&amp;quot; &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Macroglossia&lt;a name="M"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - large tongue; usually a congenital disorder (present at birth) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Maxillofacial&lt;/b&gt; &lt;br /&gt;      - pertaining to the jaws and face. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Mandibular &lt;br /&gt;      Maxillary Osteotomy and Advancement (MMOA)&lt;/b&gt; - procedure developed for &lt;br /&gt;      patients with retrolingual obstruction, patients with retropalatal and retrolingual &lt;br /&gt;      obstruction who have not responded to CPAP and uvulopalatopharyngoplasty &lt;br /&gt;      (UPPP).  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Melatonin&lt;/b&gt; &lt;br /&gt;      - hormone secreted by the brain’s pineal gland  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Micro-arousal &lt;br /&gt;      &lt;/b&gt;- partial awakening from sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Micro-sleep&lt;/b&gt; &lt;br /&gt;      - period lasting up to a few seconds during which the polysomnogram suddenly &lt;br /&gt;      shifts from waking characteristics to sleep.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Mixed &lt;br /&gt;      (sleep) apnea&lt;/b&gt; - interruption in breathing during sleep beginning as &lt;br /&gt;      a central apnea then becoming an obstructive apnea.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Monocyclic&lt;/b&gt; &lt;br /&gt;      - a single major sleep period and a single major wake period in a 24-hour &lt;br /&gt;      day. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Motor &lt;br /&gt;      Activity in Sleep&lt;/b&gt; - any muscular movement during sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Motor &lt;br /&gt;      Atonia&lt;/b&gt; – the absence of muscle activity during sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Movement &lt;br /&gt;      arousal&lt;/b&gt; - body movement associated with arousal or awakening; a sleep &lt;br /&gt;      scoring variable.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Movement &lt;br /&gt;      time&lt;/b&gt; - term used in sleep record scoring to denote when EEG and EOG &lt;br /&gt;      tracings are obscured for more than 15 seconds due to movement.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Multiple &lt;br /&gt;      sleep latency test (MSLT)&lt;/b&gt; - a series “nap tests” utilized in the assessment &lt;br /&gt;      of excessive daytime sleepiness.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Muscle &lt;br /&gt;      Tone&lt;/b&gt; – amount of tension in a muscle. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Myoclonus&lt;/b&gt; &lt;br /&gt;      - muscle contractions in the form of &amp;quot;jerks&amp;quot; or twitches.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nap&lt;/b&gt;&lt;a name="N"&gt;&lt;/a&gt; &lt;br /&gt;      - short period of planned sleep generally obtained at a time separate from &lt;br /&gt;      the major sleep period. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Narcolepsy&lt;/b&gt; &lt;br /&gt;      - sleep disorder characterized by excessive sleepiness, cataplexy, sleep &lt;br /&gt;      paralysis, hypnogogic hallucinations, and an abnormal tendency to pass directly &lt;br /&gt;      from wakefulness into REM sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nasal &lt;br /&gt;      Airflow/Nasal Ventilation&lt;/b&gt; - recording of the complete respiratory cycle &lt;br /&gt;      by measuring inspiratory and expiratory airflow  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;National &lt;br /&gt;      Commission on Sleep Disorders Research (NCSDR)&lt;/b&gt; - the commission (created &lt;br /&gt;      by the U.S. Congress in 1990) conducted a comprehensive study of the social &lt;br /&gt;      and economic impact of sleep disorders in America and made recommendations &lt;br /&gt;      based on its findings to the Congress in January 1993 &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Neurology&lt;/b&gt; &lt;br /&gt;      - branch of medicine that referring to the nervous system and its diseases &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Neurotransmitters&lt;/b&gt; &lt;br /&gt;      - endogenuous chemical components that are released from axon terminals &lt;br /&gt;      of one neuron and transmit the signal to the next neuron by combining with &lt;br /&gt;      its receptor molecules.  Neurotransmitters &lt;br /&gt;      important in the control of sleep and wakefulness include: norepinephrine, &lt;br /&gt;      serotonin, acetylcholine, dopamine, adrenaline and histamine.   &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nightmare&lt;/b&gt; &lt;br /&gt;      - unpleasant and/or frightening dream occurring in REM sleep (different &lt;br /&gt;      from a night terror)  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Night &lt;br /&gt;      Terrors&lt;/b&gt; - also known as sleep terrors, or pavor nocturnus.  Night terrors are characterized by an incomplete &lt;br /&gt;      arousal from slow wave sleep.  If, &lt;br /&gt;      the individual is awakened during a night terror, he/she is usually confused &lt;br /&gt;      and does not remember details of the event.  Night terrors are different from nightmares; if an individual is &lt;br /&gt;      awakened during a nightmare, he/she functions well and may have some recall &lt;br /&gt;      of the nightmare. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nocturia&lt;/b&gt; &lt;br /&gt;      - excessive, often frequent, urination during the night &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nocturnal&lt;/b&gt; &lt;br /&gt;      - &amp;quot;Of the night;&amp;quot; pertaining to events happening during sleep &lt;br /&gt;      or the hours of darkness. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nocturnal Confusion&lt;/b&gt; - episodes of delirium &lt;br /&gt;      and/or disorientation near or during nighttime sleep; often seen in victims &lt;br /&gt;      of Alzheimers Disease and more common in the elderly &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nocturnal sleep-related eating disorder &lt;br /&gt;      &lt;/b&gt;(NS-RED)- Getting up during the night and eating while sleepwalking. &lt;br /&gt;      No recall in the morning.&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Nocturnal &lt;br /&gt;      Enuresis (Bedwetting)&lt;/b&gt; - urinating while asleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Non-Invasive&lt;/b&gt; &lt;br /&gt;      - Medical procedure not penetrating the skin or a body cavity. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;NREM &lt;br /&gt;      or non-REM sleep&lt;/b&gt; - characterized by slower and larger brain waves and &lt;br /&gt;      little or no dream behavior;  quiet &lt;br /&gt;      sleep, slow-wave sleep;  approximately &lt;br /&gt;      80% of sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;NREM &lt;br /&gt;      Sleep Intrusion&lt;/b&gt; - brief period of NREM sleep patterns appearing in REM &lt;br /&gt;      sleep;  a portion of NREM sleep not &lt;br /&gt;      appearing in its usual sleep cycle position &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Obesity&lt;a name="O"&gt;&lt;/a&gt;-Hypoventilation &lt;br /&gt;      Syndrome&lt;/b&gt; - term applied to obese individuals hypoventilating during &lt;br /&gt;      wakefulness. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Obstructive &lt;br /&gt;      apnea&lt;/b&gt; - cessation of airflow (at least 10 seconds) in the presence of &lt;br /&gt;      continued inspiratory effort;  cessation &lt;br /&gt;      of breathing during sleep, due to a mechanical obstruction, such as a semi-collapsed &lt;br /&gt;      trachea, tongue relaxed to back of the throat, or a large among of tissue &lt;br /&gt;      in the uvula area.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Obstructive &lt;br /&gt;      Hypopnea&lt;/b&gt; - periodic and partial closure of the throat during sleep resulting &lt;br /&gt;      in reduced air exchange at the level of the mouth and/or nostril. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Ondine's &lt;br /&gt;      Curse&lt;/b&gt; - the respiratory center in the brain is unable to stimulate breathing &lt;br /&gt;      in response to an increased amount of carbon dioxide in the blood.  Ondine's Curse or central alveolar hypoventilation &lt;br /&gt;      typically worsens during sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Optimum &lt;br /&gt;      Sleep&lt;/b&gt; - average amount of sleep needed every night by an individual. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Oxygen &lt;br /&gt;      Desaturation&lt;/b&gt; - less than normal amount of oxygen carried by hemoglobin &lt;br /&gt;      in the blood;  values below 90% are &lt;br /&gt;      considered abnormal &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Oxygen &lt;br /&gt;      Saturation&lt;/b&gt; - measure of oxygen carried by hemoglobin in the blood. Normal &lt;br /&gt;      values 90% - 100%.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Oximeter &lt;br /&gt;      (Pulse)&lt;/b&gt; - gives estimates of arterial oxyhemoglobin saturation (SaO2) &lt;br /&gt;      by utilizing selected wavelengths of light to non invasively determine the &lt;br /&gt;      saturation of oxyhemoglobin (SpO2) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Oximetry &lt;br /&gt;      (Pulse)&lt;/b&gt; - continuous monitoring of oxygen saturation of arterial blood &lt;br /&gt;      from a pulse oximeter;  the sensor &lt;br /&gt;      is usually attached to the finger. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;O2&lt;/b&gt; &lt;br /&gt;      - Chemical symbol for oxygen. Criterion lowest percent O2 saturation: Greater &lt;br /&gt;      than 85%=mild, 80% to 85%=moderate, less than 80%=severe  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Parasomnia&lt;a name="P"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - an event happening during sleep, or induced or exacerbated by sleep, such &lt;br /&gt;      as sleepwalking or asthma; not a dyssomnia.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Paroxysmal &lt;br /&gt;      nocturnal dyspnea (PND)&lt;/b&gt; - respiratory distress and shortness of breath &lt;br /&gt;      due to pulmonary edema, appearing suddenly and often awakening the sleeping &lt;br /&gt;      individual.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pathological &lt;br /&gt;      Sleep&lt;/b&gt; - abnormal sleep patterns. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pavor &lt;br /&gt;      Nocturnus&lt;/b&gt; (Night Terrors) - See Night Terrors. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Perceptual &lt;br /&gt;      Disengagement&lt;/b&gt; - change in consciousness at the onset of sleep when environmental &lt;br /&gt;      stimuli are no longer perceived, and there is no longer any conscious, meaningful &lt;br /&gt;      interaction with the environment. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Periodic &lt;br /&gt;      Breathing&lt;/b&gt; - repetitive apneic pauses, common in premature infants. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Periodic &lt;br /&gt;      Limb Movement Disorder&lt;/b&gt; - also known as periodic leg movements and nocturnal &lt;br /&gt;      myoclonus. Characterized by periodic episodes of repetitive and highly stereotyped &lt;br /&gt;      limb movements occuring during sleep. The movements are often associated &lt;br /&gt;      with a partial arousal or awakening; however, the patient is usually unaware &lt;br /&gt;      of the limb movements or frequent sleep disruption.  Between the episodes, the legs are still. There &lt;br /&gt;      can be marked night-to-night variability in the number of movements or in &lt;br /&gt;      the existence of movements. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Persistent &lt;br /&gt;      Insomnia&lt;/b&gt; - continuing insomnia responding poorly to treatment. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pharynx&lt;/b&gt; &lt;br /&gt;      - area posterior to the nares and the oral cavity;  passageway for air from the nasal cavity and/or the mouth to the &lt;br /&gt;      lungs via the larynx and the trachea, for food and liquids from the mouth &lt;br /&gt;      to the esophagus &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Phase &lt;br /&gt;      advance&lt;/b&gt; - movement to a position earlier in the 24 hour sleep - wake &lt;br /&gt;      cycle of a period of sleep or wake; for example, a shift of the sleep phase &lt;br /&gt;      from 11 p.m. - 7 a.m. to 8 p.m. - 4 a.m.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Phase &lt;br /&gt;      delay&lt;/b&gt; - Phase delay is exactly the opposite of phase advance, i.e., &lt;br /&gt;      a shift later in time.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Phasic &lt;br /&gt;      (Event/Activity)&lt;/b&gt; - brain, muscle, or autonomic related event of a brief &lt;br /&gt;      and episodic nature occurring in sleep. Usually  &lt;br /&gt;      occur during REM sleep, such as eye movements and/or muscle twitches &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Photoperiod&lt;/b&gt; &lt;br /&gt;      - duration of light in a light/dark cycle. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pickwickian &lt;br /&gt;      Syndrome&lt;/b&gt; - obesity accompanied by somnolence, lethargy, chronic hypoventilation, &lt;br /&gt;      hypoxia, and secondary polycythemia (a condition marked by an abnormal increase &lt;br /&gt;      in the number of circulating red blood cells);  usually has severe obstructive sleep apnea &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pineal &lt;br /&gt;      Gland&lt;/b&gt; - gland in the brain secreting the hormone melatonin. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;PLMD-Arousal &lt;br /&gt;      Index&lt;/b&gt; - number of sleep-related periodic leg movements per hour of sleep &lt;br /&gt;      that are associated with an EEG arousal &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Polycyclic&lt;/b&gt; &lt;br /&gt;      - multiple sleep periods and wake periods in a 24-hour day. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;PO2&lt;/b&gt; &lt;br /&gt;      - partial pressure of oxygen (O2) in the blood. A value above 60 is usually &lt;br /&gt;      considered a safe level:  lower than &lt;br /&gt;      60 indicated hypoxemia and potential danger for the patient.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Polysomnogram &lt;br /&gt;      (PSG)&lt;/b&gt; - continuous and simultaneous recording of physiological variables &lt;br /&gt;      during sleep, i.e., EEG, EOG, EMG (the three basic stage scoring parameters), &lt;br /&gt;      EKG, respiratory air flow, respiratory excursion, lower limb movement, and &lt;br /&gt;      other electrophysiological variables.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Polysomnograph&lt;/b&gt; &lt;br /&gt;      - biomedical instrument for the measurement of multiple physiological variables &lt;br /&gt;      of sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Polysomnographic &lt;br /&gt;      Technologist&lt;/b&gt; - health care professional trained in performing diagnostic &lt;br /&gt;      sleep studies &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Post-Prandial &lt;br /&gt;      Drowsiness&lt;/b&gt; - sleepiness that occurs after a meal, usually lunch &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Post-Traumatic &lt;br /&gt;      Stress Disorder&lt;/b&gt; - re-experiencing of a traumatic event in the form of &lt;br /&gt;      repetitive dreams, recurrent and intrusive daytime recollections, and/or &lt;br /&gt;      dissociative flashback episodes. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Premature &lt;br /&gt;      morning awakening&lt;/b&gt; - early termination of the sleep period in a sleep &lt;br /&gt;      maintenance DIMS due to inability to return to sleep after the last of several &lt;br /&gt;      awakenings &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Prescribed &lt;br /&gt;      CPAP Pressure&lt;/b&gt; - pressure(s) or settings determined by a CPAP titration &lt;br /&gt;      sleep study, which a physician prescribes for a patient's CPAP therapy machine &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Pulse &lt;br /&gt;      Oximetry&lt;/b&gt; - non-invasive measure of oxygen saturation; that is the amount &lt;br /&gt;      of oxygen saturated in the hemoglobin in terms of percentage;  not as accurate as the values obtained from &lt;br /&gt;      an arterial blood gases (ABG) test and should only be used as a gauge of &lt;br /&gt;      oxygenation.  Normal ranges are between &lt;br /&gt;      95-100%.   &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Quiet &lt;br /&gt;      Sleep&lt;a name="Q"&gt;&lt;/a&gt;&lt;/b&gt; - The term frequently used instead of NREM sleep &lt;br /&gt;      to describe the sleep of infants. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Radiofrequency&lt;a name="R"&gt;&lt;/a&gt; &lt;br /&gt;      (RF&lt;/b&gt;) - Electromagnetic radiation in the frequency range 3 kilohertz &lt;br /&gt;      (kHz) to 300 gigahertz (GHz); considered to include microwaves and radio &lt;br /&gt;      waves.  Microwaves occupy the spectral region between &lt;br /&gt;      300 GHz and 300 MHz, while RF or radio waves include 300 MHz to 3 kHz.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Radiofrequency &lt;br /&gt;      (RF)&lt;/b&gt; Procedure (also known as Somnoplasty) - procedure for treating &lt;br /&gt;      nasal obstruction, snoring and in some cases, sleep apnea. The procedure &lt;br /&gt;      uses radiowave energy to reduce snoring and the size of the soft palate. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;RDI&lt;/b&gt; &lt;br /&gt;      - Respiratory Disturbance Index, includes all respiratory events per hour. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      sleep&lt;/b&gt;, rapid eye movement sleep - sleep characterized by the active &lt;br /&gt;      brain waves, flitting motions of the eyes, and weakness of the muscles; &lt;br /&gt;      most dreaming occurs in this stage, which accounts for about 20% of sleep &lt;br /&gt;      in adults.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Density&lt;/b&gt; - A function that expresses the frequency of eye movements per &lt;br /&gt;      unit of time during REM sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM-Associated &lt;br /&gt;      Disorders&lt;/b&gt; - Sleep disturbances that occur in REM sleep.    &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REMS &lt;br /&gt;      latency&lt;/b&gt; - The period of time in the sleep period from sleep onset to &lt;br /&gt;      the first appearance of stage REMS.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Motor Atonia&lt;/b&gt; - The active suppression of activity in the antigravity &lt;br /&gt;      and voluntary muscles during REM sleep. The muscles are completely flaccid &lt;br /&gt;      and limp. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      onset&lt;/b&gt; - designation for commencement of a REM period;  used also as a shorthand term for a sleep-onset REM period  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      period&lt;/b&gt; - REM portion of a NREM-REM cycle; early in the night it may &lt;br /&gt;      be as short as a half-minute, whereas in later cycles longer than an hour. &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      rebound or recovery&lt;/b&gt; - lengthening and increase in frequency and density &lt;br /&gt;      of REM periods, which results in an increase in REM percent above base line. &lt;br /&gt;      REM rebound follows REM deprivation once the inhibitory influence is removed &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Behavior Disorder&lt;/b&gt; (RBD)- disorder in which REM motor atonia is &lt;br /&gt;      partially or completely absent and the individual acts out the ongoing dream. &lt;br /&gt;      The behavior in REM behavior disorder is often correlates with the ongoing, &lt;br /&gt;      hallucinatory REM dream episode. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Episode&lt;/b&gt; - REM sleep portion of a NREM-REM sleep cycle. Early in &lt;br /&gt;      the first sleep period, episodes may be only several minutes in duration. &lt;br /&gt;      Later REM episodes almost are always longer, 20 to 30 minutes up to an hour. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Intrusion&lt;/b&gt; - brief interval of REM sleep appearing out of its usual &lt;br /&gt;      positioning in the NREM-REM sleep cycle. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Latency&lt;/b&gt; - interval from sleep onset to the first appearance of &lt;br /&gt;      REM sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Onset&lt;/b&gt; - designation for the first epoch of a REM sleep episode &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Percent&lt;/b&gt; - proportion of total sleep time occupied by REM sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;REM &lt;br /&gt;      Sleep Rebound &lt;/b&gt;- compensatory increase in REM sleep following experimental &lt;br /&gt;      reduction. Extension of time in, and an increase in frequency and density &lt;br /&gt;      of REM sleep episodes;  usually an &lt;br /&gt;      increase in REM sleep percent of total sleep time above baseline values &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Respiratory &lt;br /&gt;      Care Practitioner (RCP)&lt;/b&gt; - licensed health care professional specifically &lt;br /&gt;      trained in cardiopulmonary assessment, diagnostics, therapy administration, &lt;br /&gt;      and patient education, including the identification and treatment of sleep &lt;br /&gt;      disorders &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Restless Legs Syndrome (RLS)&lt;/b&gt; - sleep &lt;br /&gt;      disorder characterized by a deep creeping, or crawling sensation in the &lt;br /&gt;      legs that tends to occur when an individual is not moving. There is an almost &lt;br /&gt;      irresistible urge to move the legs;  the sensations are relieved by movement. &lt;br /&gt;      &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Restlessness &lt;br /&gt;      (Referring to Quality of Sleep)&lt;/b&gt; - Persistent or recurrent body movements, &lt;br /&gt;      arousals, and/or brief awakenings in the course of sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sedatives&lt;a name="S"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - compounds tending to calm, and reduce nervousness or excitement and foster &lt;br /&gt;      sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sedentary &lt;br /&gt;      Situation&lt;/b&gt; - not requiring physical activity, e.g. working at a desk, &lt;br /&gt;      sitting in a meeting or in a theater, watching television. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Septoplasty &lt;br /&gt;      &lt;/b&gt;- surgery on the nasal septum (dividing the nasal passage) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Serotonin&lt;/b&gt; &lt;br /&gt;      - neurotransmitter in the brain that modulates mood, appetite, sexual activity, &lt;br /&gt;      aggression, body temperature and sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Shiftwork&lt;/b&gt; &lt;br /&gt;      - working hours outside of the conventional daytime hours of 9:00 a.m. to &lt;br /&gt;      5:00 p.m. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep&lt;/b&gt; &lt;br /&gt;      - a state marked by lessened consciousness, lessened movement of the skeletal &lt;br /&gt;      muscles, and slowed-down metabolism  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Apnea&lt;/b&gt; - cessation of breathing for 10 or more seconds during sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      architecture &lt;/b&gt;- NREM/REM stage and cycle infrastructure of sleep understood &lt;br /&gt;      from the vantage point of the quantitative relationship of these components &lt;br /&gt;      to each other  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      cycle&lt;/b&gt; - synonymous with NREM-REM cycle &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Debt&lt;/b&gt; - result of recurrent sleep deprivation which occurs over time &lt;br /&gt;      when an individual does not experience a sufficient amount of the restorative &lt;br /&gt;      daily sleep that is required to maintain a sense of feeling rested and refreshed.  &lt;br /&gt;      . &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Deprivation&lt;/b&gt; - acute or chronic lack of sufficient sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Disorders&lt;/b&gt; - broad range of illnesses arising from many causes, including, &lt;br /&gt;      dysfunctional sleep mechanisms, abnormalities in physiological functions &lt;br /&gt;      during sleep, abnormalities of the biological clock, and sleep disturbances &lt;br /&gt;      that are induced by factors extrinsic to the sleep process &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      efficiency&lt;/b&gt; (SE) - proportion of sleep in the period potentially filled &lt;br /&gt;      by sleep--ratio of total sleep time to time in bed &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Episode&lt;/b&gt; - interval of sleep that may be voluntary or involuntary &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Extension&lt;/b&gt; - extending sleep time by increasing the time in bed &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Fragmentation&lt;/b&gt; - brief arousals occurring throughout the night, reducing &lt;br /&gt;      the total amount of time spent in the deeper levels of sleep.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      hygiene&lt;/b&gt; - conditions and practices that promote continuous and effective &lt;br /&gt;      sleep, including regularity of bedtime and arise time; conforming time spent &lt;br /&gt;      in bed to the time necessary for sustained and individually adequate sleep &lt;br /&gt;      (i.e., the total sleep time sufficient to avoid sleepiness when awake);  restriction of alcohol and caffeine beverages &lt;br /&gt;      in the period prior to bedtime;  employment &lt;br /&gt;      of exercise, nutrition, and environmental factors so that they enhance, &lt;br /&gt;      not disturb, restful sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Hyperhydrosis&lt;/b&gt; - excessive sweating during sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Inertia&lt;/b&gt; - feelings of grogginess and/or sleepiness that persist longer &lt;br /&gt;      than 10 to 20 minutes after waking up &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      interruption&lt;/b&gt; - breaks in the sleep architecture resulting in arousal &lt;br /&gt;      and wakefulness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      latency&lt;/b&gt; - time period measured from &amp;quot;lights out,&amp;quot; or bedtime, &lt;br /&gt;      to the beginning of sleep  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      log&lt;/b&gt; (-diary) - daily, written record of an individual's sleep-wake pattern &lt;br /&gt;      containing such information as time of retiring and arising, time in bed, &lt;br /&gt;      estimated total sleep period, number and duration of sleep interruptions, &lt;br /&gt;      quality of sleep, daytime naps, use of medications or caffeine beverages, &lt;br /&gt;      nature of waking activities, and other data &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep-maintenance &lt;br /&gt;      DIMS or insomnia&lt;/b&gt; - disturbance in maintaining sleep once achieved;  persistently interrupted sleep without difficulty &lt;br /&gt;      falling asleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Mentation&lt;/b&gt; - thoughts, feelings, images, perceptions, hallucinations, &lt;br /&gt;      and active dreams taking place during sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      onset&lt;/b&gt; - transition from wake to sleep, normally into NREM stage 1 (but &lt;br /&gt;      in certain conditions, such as infancy and narcolepsy, into stage REMS) &lt;br /&gt;       &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Onset Imagery&lt;/b&gt; - images and experiences during the moments following &lt;br /&gt;      the transition from wake to sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep-onset REM period&lt;/b&gt; - atypical beginning &lt;br /&gt;      of sleep by entrance directly into stage REM &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep paralysis&lt;/b&gt; - waking and not being &lt;br /&gt;      able to move for a short period of time, usually occurs out of REM (dream) &lt;br /&gt;      sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      pattern&lt;/b&gt; (24 hour sleep-wake pattern) - individual's clock hour schedule &lt;br /&gt;      of bedtimes and rise times as well as nap behavior: may also include time &lt;br /&gt;      and duration of sleep interruptions  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleeping &lt;br /&gt;      Pills&lt;/b&gt; - compounds that have a sedative effect,  &lt;br /&gt;      used to produce sleepiness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Related Accidents&lt;/b&gt; - accidents caused by individuals who were sleep deprived &lt;br /&gt;      and who, as a result, had impaired judgment &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Restriction&lt;/b&gt; - limitation of the number of hours in bed &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      spindle&lt;/b&gt; - episodically appearing, spindle-shaped aggregate of 12-14 &lt;br /&gt;      Hz waves with a duration of 0.5-1.5 seconds, one of the identifying EEG &lt;br /&gt;      phenomena of NREM stage 2 sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      Stage Demarcation&lt;/b&gt; - significant polysomnographic characteristics that &lt;br /&gt;      distinguish the boundaries of the sleep stages. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      stage NREM &lt;/b&gt;-  major sleep state &lt;br /&gt;      apart from REMS; comprises sleep stages 1-4 &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      stage 1&lt;/b&gt; - a stage of NREM sleep occurring after wake. Its criteria consist &lt;br /&gt;      of a low-voltage EEG with slowing to theta frequencies, alpha activity less &lt;br /&gt;      than 50%, EEG vertex spikes, and slow rolling eye movements; no sleep spindles, &lt;br /&gt;      K-complexes, or REMS.  Stage 1 normally &lt;br /&gt;      assumes 4-5% of total sleep.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      stage 2&lt;/b&gt; - a stage of NREM sleep characterized by sleep spindles and &lt;br /&gt;      K complexes against a relatively low-voltage, mixed-frequency EEG background; &lt;br /&gt;      high-voltage delta waves may comprise up to 20% of stage 2 epochs; usually &lt;br /&gt;      accounts for 45-55% of total sleep time.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      stage 3&lt;/b&gt; - a stage of NREM sleep defined by at least 20 and not more &lt;br /&gt;      than 50% of the period (30 second epoch) consisting of EEG waves less than &lt;br /&gt;      2 Hz and more than 75 uV (high -amplitude delta waves); a &amp;quot;delta&amp;quot; &lt;br /&gt;      sleep stage; with stage 4, it constitutes &amp;quot;deep &amp;quot;NREM sleep;  appears usually only in the first third of the sleep period; usually &lt;br /&gt;      comprises 4-6% of total sleep time.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      stage 4&lt;/b&gt;  - all statements concerning &lt;br /&gt;      NREM stage 3 apply to stage 4 except that high-voltage, slow EEG waves, &lt;br /&gt;      cover 50% or more of the record;  NREM &lt;br /&gt;      stage 4 usually takes up 12-15% of total sleep time.  &lt;br /&gt;      Somnambulism, sleep terror, and sleep-related enuresis episodes generally &lt;br /&gt;      start in stage 4 or during arousals from this stage &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep stage REM&lt;/b&gt; - the stage of sleep &lt;br /&gt;      found in all mammal studies, including man, in which brain activity is extensive, &lt;br /&gt;      brain metabolism is increased, and vivid hallucinatory imagery, or dreaming &lt;br /&gt;      occurs (in humans).  Also called &amp;quot;paradoxical sleep&amp;quot; because, &lt;br /&gt;      in the face of this intense excitation of the CNS and presence of spontaneous &lt;br /&gt;      rapid eye movements, resting muscle activity is suppressed.  The EEG is &lt;br /&gt;      a low-voltage, fast-frequency, non alpha record.  Stage REMS is usually &lt;br /&gt;      20-25% of total sleep time. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      structure &lt;/b&gt;- similar to sleep architecture.  &lt;br /&gt;      Sleep structure, in addition to encompassing sleep stage and cycle &lt;br /&gt;      relationships, assesses the within-stage qualities of the EEG and other &lt;br /&gt;      physiological attributes.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleepiness&lt;/b&gt; &lt;br /&gt;      (somnolence, drowsiness) - difficulty in maintaining the wakeful state so &lt;br /&gt;      that the individual falls asleep if not actively kept aroused;  not simply a feeling of physical tiredness or &lt;br /&gt;      listlessness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep &lt;br /&gt;      talking&lt;/b&gt; - talking in sleep takes place during stage REMS, representing &lt;br /&gt;      a motor breakthrough of dream speech, or in the course of transitory arousals &lt;br /&gt;      from NREMS and other stages.  Full &lt;br /&gt;      consciousness is not achieved and no memory of the event remains.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleepwalker &lt;br /&gt;      or Sleepwalking&lt;/b&gt; - individual subject to somnambulism (one who walks &lt;br /&gt;      while sleeping).  Sleepwalking typically &lt;br /&gt;      occurs in the first third of the night during deep NREM sleep (stages 3 &lt;br /&gt;      and 4). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep-wake, 24 hour cycle&lt;/b&gt; - the clock &lt;br /&gt;      hour relationships of the major sleep and wake phases in the 24 hour cycle: &lt;br /&gt;      similar to sleep pattern. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep-wake &lt;br /&gt;      shift&lt;/b&gt; (-change, -reversal) – sleep wholly or partially moved to a time &lt;br /&gt;      of customary waking activity, and the latter is moved to the habitual sleep &lt;br /&gt;      period; common in jet lag and shift work.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sleep-Wake &lt;br /&gt;      Transition Disorder&lt;/b&gt; - disorder occuring during the transition from wakefulness &lt;br /&gt;      to sleep or from one sleep stage to another;  &lt;br /&gt;      a form of parasomnia &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Slow &lt;br /&gt;      wave sleep (SWS)&lt;/b&gt; - sleep stages 3 and 4 &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;SmartPAP &lt;br /&gt;      (Smart CPAP&lt;/b&gt;) - (Smart [Continuous] Positive Airway Pressure) Medical &lt;br /&gt;      device used in the treatment of obstructive sleep apnea providing preset &lt;br /&gt;      levels of continuous airflow, and automatically adjusting to keep the breathing &lt;br /&gt;      passages open by sensing changes in airway integrity. The air flows from &lt;br /&gt;      the device through a tube that connects to a nose or face mask. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Snoring&lt;/b&gt; &lt;br /&gt;      - noise produced primarily with inspiratory respiration during sleep owing &lt;br /&gt;      to vibration of the soft palate and the pillars of the oropharyngeal inlet.  Many snorers have incomplete obstruction of &lt;br /&gt;      the upper airway, and may develop obstructive sleep apnea.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Soft &lt;br /&gt;      Palate&lt;/b&gt; - membranous and muscular fold suspended from the posterior margin &lt;br /&gt;      of the hard palate and partially separating the oral cavity from the pharynx &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Somatic &lt;br /&gt;      Complaints&lt;/b&gt; - awareness of pain or problems in the body &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Somnambulism&lt;/b&gt; &lt;br /&gt;      - walking while asleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Somnifacient&lt;/b&gt; &lt;br /&gt;      - inducing sleep; hypnotic, as in a drug &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Somnolence&lt;/b&gt; &lt;br /&gt;      - prolonged drowsiness or sleepiness. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Somnoplasty&lt;/b&gt; &lt;br /&gt;      - commercial name for radiofrequency treatment of certain sleep disorders &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Soporific&lt;/b&gt; &lt;br /&gt;      - causing or tending to cause sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Spindle &lt;br /&gt;      REMS&lt;/b&gt; - condition in which sleep spindles persist atypically in REMS; &lt;br /&gt;      seen in chronic DIMS conditions &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Stanford &lt;br /&gt;      Sleepiness Scale (SSS)&lt;/b&gt; - 7-point rating scale consisting of seven numbered &lt;br /&gt;      statements describing subjective levels of sleepiness/alertness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Subjective &lt;br /&gt;      Sleepiness&lt;/b&gt; - feelings of sleepiness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Substance &lt;br /&gt;      Abuse&lt;/b&gt; - excessive use of alcohol or drug;  &lt;br /&gt;      substances can cause sleep disturbances &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Subwakefulness &lt;br /&gt;      syndrome&lt;/b&gt; - syndrome defined as a defect in the CNS support system for &lt;br /&gt;      waking.  The few individuals reported &lt;br /&gt;      with subwakefulness syndrome have daytime drowsiness and daytime sleep episodes &lt;br /&gt;      that are always composed of NREMS stages 1 or 2.  The naps occur repetitively &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Sudden &lt;br /&gt;      Infant Death Syndrome (SIDS)&lt;/b&gt; -  sudden &lt;br /&gt;      and unexpected death of an apparently healthy infant, whose death remains &lt;br /&gt;      unexplained after the performance of an adequate postmortem investigation.  Death usually occurs during sleep.  SIDS is a classification that is used to describe &lt;br /&gt;      a deceased infant. It is not a disease, nor can it be a diagnosis for a &lt;br /&gt;      living baby. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Synchronization&lt;/b&gt; &lt;br /&gt;      - chronobiological term used to indicate that two or more rhythms recur &lt;br /&gt;      with the same phase relationship.  In &lt;br /&gt;      an EEG tracing, the term is used to indicate an increased amplitude with &lt;br /&gt;      an occasional decreased frequency of the dominant activities. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Synchrony&lt;/b&gt; &lt;br /&gt;      - scheduling sleep to synchronize with the biological clock &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tachycardia&lt;a name="T"&gt;&lt;/a&gt;&lt;/b&gt; &lt;br /&gt;      - rapid heart rate, usually defined by a pulse rate of over 100 beats per &lt;br /&gt;      minute (bpm). &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Thermocouples&lt;/b&gt; &lt;br /&gt;      - small devices placed near the nostrils or mouth to measure air flow by &lt;br /&gt;      sensing temperature changes; expired air is warmer than inspired air.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Thermoregulation&lt;/b&gt; &lt;br /&gt;      - regulation of body temperature in mammals. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Theta &lt;br /&gt;      waves&lt;/b&gt; - EEG activity with a frequency of 4-8 Hz &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Thoracic &lt;br /&gt;      Excursion&lt;/b&gt; - thoracic (chest) movement, indicating respiratory effort.  Usually measured by the placement of a sensor &lt;br /&gt;      band, which includes a strain gauge around the chest.  The sensor band records chest wall movement &lt;br /&gt;      associated with respirations.. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tidal &lt;br /&gt;      Volume&lt;/b&gt; -  amount of air that &lt;br /&gt;      passes in and out of the lungs in an ordinary breath;  &lt;br /&gt;      usually expressed in liters &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Titration&lt;/b&gt; &lt;br /&gt;      - progressive, stepwise increase in CPAP pressure applied during a polysomnogram &lt;br /&gt;      to establish the optimal treatment pressure &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tolerance&lt;/b&gt; &lt;br /&gt;      - in pharmacology, refers to the reduced responsiveness to a drug's action &lt;br /&gt;      as the result of previous continued and/or multiple exposure &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tonic &lt;br /&gt;      (Event/Activity)&lt;/b&gt; - brain, muscle, or autonomic events, which are continuous.  &lt;br /&gt;      Usually refers to continuous activity (e.g. muscle atonia) during &lt;br /&gt;      REM sleep. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tonsils&lt;/b&gt; &lt;br /&gt;      - pair of prominent masses of lymphoid tissue that are located opposite &lt;br /&gt;      each other in the throat between the anterior and posterior pillars of the &lt;br /&gt;      fauces (the narrow passage from the mouth to the pharynx situated between &lt;br /&gt;      the soft palate and the base of the tongue). Composed of lymph follicles &lt;br /&gt;      grouped around one or more deep crypts.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tonsillectomy&lt;/b&gt; &lt;br /&gt;      - surgical removal of the tonsils &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Total &lt;br /&gt;      Recording Time&lt;/b&gt; - duration of time from sleep onset to final awakening. &lt;br /&gt;      I n addition to total sleep time, it is comprised of the time taken up by &lt;br /&gt;      wake periods and movement time until wake-up. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Total &lt;br /&gt;      sleep period&lt;/b&gt; - period of time measured from sleep onset to final awakening. &lt;br /&gt;      In addition to total sleep time, it is comprised of the time taken up by &lt;br /&gt;      arousals and movement time until wake-up  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Total &lt;br /&gt;      sleep time (TST)&lt;/b&gt; - amount of actual sleep time in a sleep period; equal &lt;br /&gt;      to total sleep period less movement and awake time.  Total sleep time is the total of all REMS and NREMS in a sleep period. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tracheotomy&lt;/b&gt; &lt;br /&gt;      - surgical procedure to create an opening in the trachea (windpipe) so that &lt;br /&gt;      one can breathe  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tracheostomy&lt;/b&gt; &lt;br /&gt;      - refers to the opening in the trachea. As a treatment for severe obstructive &lt;br /&gt;      sleep apnea, a tube to assist oxygenation and ventilation and/or to overcome &lt;br /&gt;      an obstruction in the airway located superiorly. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Transducer&lt;/b&gt; &lt;br /&gt;      - device designed to convert energy from one form to another &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Transient &lt;br /&gt;      Arousals &lt;/b&gt;- brief awakenings from sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Transient &lt;br /&gt;      Insomnia&lt;/b&gt; - difficulty sleeping for only a few nights &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tricyclic &lt;br /&gt;      Antidepressants&lt;/b&gt; - medication for depression.  &lt;br /&gt;      Most tricyclic antidepressants also reduce REM sleep;  also used to control cataplectic attacks, hypnogogic &lt;br /&gt;      hallucinations, and sleep paralysis. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Tumescence &lt;br /&gt;      (penile) &lt;/b&gt;- hardening and expansion of the penis: penile erection. Commonly &lt;br /&gt;      referred to as nocturnal penile tumescence (NPT) in sleep recordings.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Turbinate&lt;/b&gt; &lt;br /&gt;      - small, shelf-like, cartilaginous structures covered by mucous membranes, &lt;br /&gt;      which protrude into the nasal airway to help warm, humidify, and cleanse &lt;br /&gt;      inhaled air on its way to the lungs. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Twilight &lt;br /&gt;      Zone&lt;/b&gt; - slang popular term to describe the waking state of individuals &lt;br /&gt;      whose MSLT scores are 5 minutes or less. Such individuals are usually sleep &lt;br /&gt;      deprived or suffer from a sleep disorder. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Twitch &lt;br /&gt;      (Body Twitch)&lt;/b&gt; - very small body movement such as a local foot or finger &lt;br /&gt;      jerk which is not usually associated with an arousal. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Unattended&lt;a name="U"&gt;&lt;/a&gt; &lt;br /&gt;      CPAP Titration Study&lt;/b&gt; - sleep study that is usually performed in the &lt;br /&gt;      home, after determining that a patient has a sleep related breathing disorder &lt;br /&gt;      such as OSA or Upper Airway Resistance Syndrome, and is likely to benefit &lt;br /&gt;      from CPAP therapy.   &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Unintended &lt;br /&gt;      Sleep Episode&lt;/b&gt; - sleep episode that is not planned and may happen during &lt;br /&gt;      an activity in which such an episode is hazardous, such as when driving &lt;br /&gt;      a car or working with machinery &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Upper &lt;br /&gt;      Airway&lt;/b&gt; - part of the respiratory anatomy that includes the nose, nostrils, &lt;br /&gt;      sinus passages, septum, turbinates;  the &lt;br /&gt;      tongue, jaws, hard and soft palate, muscles of the tongue and throat, etc. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Upper &lt;br /&gt;      Airway Resistance Syndrome (UARS)&lt;/b&gt; - part of the spectrum of obstructive &lt;br /&gt;      sleep-related breathing disorders in which repetitive increases in resistance &lt;br /&gt;      to airflow in the upper airway lead to brief arousals and daytime fatigue.  Apneas and hypopneas (see RDI) may be totally &lt;br /&gt;      absent.  Blood oxygen levels can &lt;br /&gt;      be in the normal range. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Uvula&lt;/b&gt; &lt;br /&gt;      - small soft structure hanging from the bottom of the soft palate in the &lt;br /&gt;      midline above the back of the tongue.   &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Uvulopalatopharyngoplasty &lt;br /&gt;      (UPPP)&lt;/b&gt; - also abbreviated as UPP or UP3 this operation is performed &lt;br /&gt;      on the throat to treat snoring and sleep apnea.  &lt;br /&gt;      UPPP is an accepted means of surgical treatment has a curative rate &lt;br /&gt;      of less than 50%.  Scientific evidence &lt;br /&gt;      suggests that UPPP works best in retropalatal and combination retropalatal &lt;br /&gt;      and retrolingual obstruction  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Wake &lt;br /&gt;      time&lt;a name="W"&gt;&lt;/a&gt;&lt;/b&gt;  - total &lt;br /&gt;      time that is scored awake in a polysomnogram occurring between sleep onset &lt;br /&gt;      and final wake-up &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;White &lt;br /&gt;      Noise &lt;/b&gt;- mixture of sound waves extending over a wide frequency range &lt;br /&gt;      that may be used to mask unwanted noise that may interfere with sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Wilkinson &lt;br /&gt;      Addition Test&lt;/b&gt; - performance test;  numbers &lt;br /&gt;      added for one hour. Often included in a battery of tests to measure the &lt;br /&gt;      impact of acute or chronic sleep loss. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Withdrawal&lt;/b&gt; &lt;br /&gt;      - effects experienced when a patient stops taking sleeping pills &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;            &lt;p&gt;&lt;font face="Arial" size="-1"&gt;&lt;b&gt;Zeitgeber&lt;a name="Z"&gt;&lt;/a&gt; &lt;br /&gt;      &lt;/b&gt;- environmental time cue that entrains biological rhythms to a specific &lt;br /&gt;      periodicity.  Known Zeitgebers are &lt;br /&gt;      light, melatonin and physical activity.  &lt;br /&gt;      To be effective, these signals must occur when the biological clock &lt;br /&gt;      is in a responsive phase. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;br /&gt;            &lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;br /&gt;          &lt;br /&gt;        &lt;br /&gt;        &lt;blockquote&gt;&lt;br /&gt;          &lt;blockquote&gt;&lt;br /&gt;            &lt;div&gt; &lt;br /&gt;              &lt;h3&gt;&lt;font face="Arial" size="-1"&gt;&lt;font color="#990099"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;font color="#663333"&gt;Abbreviations&lt;/font&gt;&lt;a name="ABB"&gt;&lt;/a&gt;&lt;/font&gt;&lt;/font&gt;&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;            &lt;/div&gt;&lt;br /&gt;          &lt;/blockquote&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1"&gt;&lt;b&gt;&lt;font face="Arial, Helvetica, sans-serif"&gt;AB&lt;/font&gt;&lt;/b&gt;&lt;font face="Arial, Helvetica, sans-serif"&gt; - Automatic Behavior&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;             &lt;b&gt;AD&lt;/b&gt; - Alzheimer's Disease&lt;/font&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;ADA&lt;/b&gt; - Americans with Disabilities Act &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;ADD&lt;/b&gt; - Attention Deficit Disorder &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;ADHD&lt;/b&gt; - Attention Deficit Hyperactivity Disorder &lt;br&gt;&lt;br /&gt;            &lt;b&gt;&lt;br&gt;&lt;br /&gt;            AERMS&lt;/b&gt; - ambulatory electrocardiogram-respiration monitoring system&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;b&gt;&lt;/b&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;AHI &amp;#8211; &lt;/b&gt;Apnea/Hypopnea Index &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;AI&lt;/b&gt; &amp;#8211; Apnea Index &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;APAP&lt;/b&gt; &lt;b&gt;(Auto-CPAP)&lt;/b&gt; - auto-titrating, self-adjusting device&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;BDZ&lt;/b&gt; &amp;#8211; Benzodiazepine&lt;br&gt;&lt;br /&gt;            &lt;b&gt;&lt;br&gt;&lt;br /&gt;            Bi-PAP (BPAP)&lt;/b&gt; - Trademark name of a Bi-Level cpap machine.&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;b&gt;BMI&lt;/b&gt; &amp;#8211; Body Mass Index&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;BPM&lt;/b&gt; &amp;#8211; Beats per minute &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;C&lt;/b&gt; - Cataplexy &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;CDC&lt;/b&gt; - Center for Disease Control &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;CFIDS&lt;/b&gt; - Chronic Fatigue Immune Dysfunction Syndrome &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;CFS&lt;/b&gt; - Chronic Fatigue Syndrome &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;b&gt;CHF&lt;/b&gt; - Congestive Heart Failure &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;CNS&lt;/b&gt; &amp;#8211; Central nervous system &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;CPAP&lt;/b&gt; - Continuous Positive Airway Pressure (a nasal device to relieve obstructed breathing in a sleeping patient) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;cps&lt;/b&gt; &amp;#8211; cycles per second&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;             &lt;b&gt;CSR&lt;/b&gt; &amp;#8211; Cheyne-Stokes respiration &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;DIMS&lt;/b&gt; &amp;#8211; Disorders of Initiating and Maintaining Sleep &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;DME&lt;/b&gt; - Durable Medical Equipment &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;DOES&lt;/b&gt; &amp;#8211; Disorders of Excessive Somnolence &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;DSPS&lt;/b&gt; - Delayed Sleep Phase Syndrome&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;Dx&lt;/b&gt; - Diagnosis &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;EDS&lt;/b&gt; - Excessive Daytime Sleepiness &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;EEG&lt;/b&gt; &amp;#8211; Electroencephalogram &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;EH&lt;/b&gt; - Essential Hypersomnia &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;EKG - &lt;/b&gt;Electrocardiogram &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;EMG&lt;/b&gt; &amp;#8211; Electromyogram&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;ENT&lt;/b&gt; &amp;#8211; Ear, nose, and throat&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;EOG&lt;/b&gt; &amp;#8211; Electro-oculogram &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font face="Arial, Helvetica, sans-serif" size="-1"&gt;&lt;b&gt;EPAP&lt;/b&gt; - Expiratory Positive Airway Pressure &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;ENT&lt;/b&gt; - Ear, Nose, and Throat &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;GABA&lt;/b&gt; - Gamma-Amniobutyric Acid &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;GERD &amp;#8211; &lt;/b&gt;Gastroesophageal Reflux Disease &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;GHB&lt;/b&gt; - Gammahydroxybutyrate (a substance occurring naturally in the brain.&amp;nbsp; To be sold as Xyrem) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;HH&lt;/b&gt; - Hypnogogic Hallucinations &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;HLA&lt;/b&gt; - Human Leukocyte Antigen &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;Hz&lt;/b&gt; - Hertz (frequency)&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;Hx&lt;/b&gt; - Medical History&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;IH&lt;/b&gt; - Idiopathic Hypersomnia &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;IPAP&lt;/b&gt; - Inspiratory Positive Airway Pressure &lt;b&gt;&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            IRM&lt;/b&gt; - Institute of Respiratory Medicine&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;ITS&lt;/b&gt; - I'm Tired Syndrome &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;LAUP - &lt;/b&gt;Laser assisted uvulopalatoplasty &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;LMN - &lt;/b&gt;Letter of Medical Necessity &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;LTD&lt;/b&gt; - Long Term Disability &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;LO&lt;/b&gt; - Lights Out (beginning of sleep recording)&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MAO&lt;/b&gt; - Monoamine Oxidase (an enzyme in the brain tissue) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MAOI&lt;/b&gt; - Monoamine Oxidase inhibitor (a class of anti-depressant.MHC) &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;MIRS&lt;/b&gt; - mandibular inclined repositioning splint&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MRI&lt;/b&gt; - Magnetic Resonance Imagry &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MHC&lt;/b&gt; - Major Histocompatibility Complex &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MMOA&amp;nbsp;(MMA) - &lt;/b&gt;Mandibular Maxillary Osteotomy and Advancement&lt;b&gt; &lt;/b&gt; &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MSLT&lt;/b&gt; - Multiple Sleep Latency Test &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;MWT&lt;/b&gt; - maintenance of wakefulness test &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;N&lt;/b&gt; &amp;#8211; Narcolepsy &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;NCSDR - &lt;/b&gt;National Commission on Sleep Disorders Research &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;NN&lt;/b&gt; - Narcolepsy Network &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;NMH&lt;/b&gt; - Neurally Mediated Hypotension &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;NPT&lt;/b&gt; &amp;#8211; Nocturnal Penile Tumescence &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;NREM&lt;/b&gt; &amp;#8211; Non-Rapid Eye Movement (sleep)&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;NS-RED&lt;/b&gt; &amp;#8211; Nonturnal sleep related eating disorder&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;OCD&lt;/b&gt; - Obsessive Compulsive Disorder &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;ODI&lt;/b&gt; - Oxygen desaturation index&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;OLP&lt;/b&gt; - Online Psych &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;O2 - &lt;/b&gt;Oxygen&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;OSA&lt;/b&gt; - Obstructive sleep apnea&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;OSAS&lt;/b&gt; - Obstructive sleep apnea syndrome &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;PCP&lt;/b&gt; - Primary Care Physician &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PET&lt;/b&gt; - Positron Emission Tomography &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PLMD&lt;/b&gt; - Periodic Leg Movement Disorder&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PLMS&lt;/b&gt; - Periodic Leg Movements of Sleep&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PND&lt;/b&gt; &amp;#8211; Paroxsymal Nocturnal Dyspnea &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PO2 &lt;/b&gt;- partial pressure of oxygen (O2) in the blood. &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PSG&amp;nbsp; - &lt;/b&gt;Polysomnogram  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PTSD&lt;/b&gt; - post traumatic stress disorder &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PWC&lt;/b&gt; - Persons w/CFIDS &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PWN&lt;/b&gt; - Person (People) with Narcolepsy &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;PWON&lt;/b&gt; - Person (People) without Narcolepsy &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;POPWN&lt;/b&gt; - Parent of a person w/ Narcolepsy&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;PS&lt;/b&gt; &amp;#8211; Paradoxical  Sleep&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;QS&lt;/b&gt; &amp;#8211; Quiet Sleep&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;RERA&lt;/b&gt; &amp;#8211; Respiratory effort-related arousal&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;RBD&lt;/b&gt; &amp;#8211; Rem Behavior Disorder&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;RCP&lt;/b&gt; &amp;#8211; Respiratory Care Practitioner &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;RDI&lt;/b&gt; &amp;#8211; Respiratory Disturbance Index &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;REM&lt;/b&gt; - Rapid Eye Movement (sleep)&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;REML&lt;/b&gt; &amp;#8211; REM latency &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;RF&lt;/b&gt; - Radiofrequency &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;RLS&lt;/b&gt; - Restless Leg Syndrome&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;R/O&lt;/b&gt; - Rule out &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;RSD&lt;/b&gt; - Reflex Sympathetic Dystrophy &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;Rx&lt;/b&gt; - Prescription &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font face="Arial, Helvetica, sans-serif" size="-1"&gt;&lt;b&gt;SA&lt;/b&gt; - Sleep apnea&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SAD&lt;/b&gt; - Seasonal Affective Disorder &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SaO2&lt;/b&gt; - % of normal  Oxygen level  in the blood.  &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;br /&gt;            &lt;br /&gt;            &lt;b&gt;SAS&lt;/b&gt; - Sleep Apnea Syndrome&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SAHS&lt;/b&gt; - Sleep apnea/hypopnoea syndrome&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SDB&lt;/b&gt; - Sleep disordered breathing&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SEGS &lt;/b&gt;&amp;#8211; Number of REM Segments &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SEI&lt;/b&gt; &amp;#8211; Sleep efficiency index &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SEM&lt;/b&gt; &amp;#8211; Slow Eye Movement &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SIDS&lt;/b&gt; &amp;#8211; Sudden Infant Death Syndrom&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SL&lt;/b&gt; &amp;#8211; Sleep latency &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SO&lt;/b&gt; &amp;#8211; Sleep onset &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SOREM&lt;/b&gt; - Sleep onset REM &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SOPWN&lt;/b&gt; - Spouse of a PWN &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SP&lt;/b&gt; - Sleep Paralysis &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SPT&lt;/b&gt; &amp;#8211; Sleep Period Time &lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;Squib&lt;/b&gt; - Use of sensitive, superconductor, Josephson junction detectors to map brain activity&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SRBD&lt;/b&gt; - Sleep-related breathing disorder&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SRRD&lt;/b&gt; - Sleep-related respiratory disturbance&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SSDB&lt;/b&gt; - Social Security Disability Benefits &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SSI &lt;/b&gt;- Supplemental Security Income &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SSRI &lt;/b&gt;- Selective Serotonin Reuptake Inhibitor (the family of anti-depressants that include Prozac, Zoloft and Wellbutrin among others).&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;             &lt;b&gt;SSS &lt;/b&gt;- Stanford Sleepiness Scale &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;STD&lt;/b&gt; - Short Term Disability *OR* Sexually Transmitted Disease &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SWL&lt;/b&gt; &amp;#8211; Slow wave latency &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;SWS&lt;/b&gt; &amp;#8211; Slow wave sleep&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;SWDS&lt;/b&gt; &amp;#8211; Sleep-wake schedule disorder&lt;/font&gt;&lt;font size="-1"&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;Sz&lt;/b&gt; &amp;#8211; Schizophrenia &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;S1-S4&lt;/b&gt; &amp;#8211; Sleep Stages 1-4&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;             &lt;b&gt;T&amp;amp;A&lt;/b&gt; &amp;#8211; Tonsillectomy and adenoidectomy&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;b&gt;TB&lt;/b&gt; &amp;#8211; Body Temperature&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;TCA&lt;/b&gt; &amp;#8211; Tricyclic antidepressant &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TIB&lt;/b&gt; &amp;#8211; Time in Bed&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;TLC&lt;/b&gt; &amp;#8211; Total Lung Capacity &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TMT&lt;/b&gt; &amp;#8211; Total Movement Time&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;Trec&lt;/b&gt; &amp;#8211; Rectal temperature&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;TRD&lt;/b&gt; - Tongue retaining device &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TRT&lt;/b&gt; - Total recording time&lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TREM&lt;/b&gt; &amp;#8211; Total REM Time &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TST&lt;/b&gt; &amp;#8211; Total Sleep Time &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TSW&lt;/b&gt; &amp;#8211; Total Slow Wave Sleep (Stage 3 and 4) &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TT &amp;#8211; &lt;/b&gt;Total Time &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;TWT &lt;/b&gt;&amp;#8211; Total Wake Time &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;Tx&lt;/b&gt; - Treatment &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;UARS&lt;/b&gt; &amp;#8211; Upper Airway Resistance Syndrome &lt;/font&gt;&lt;/p&gt;&lt;br /&gt;          &lt;p&gt;&lt;font size="-1" face="Arial, Helvetica, sans-serif"&gt;&lt;b&gt;UPPP - &lt;/b&gt;Uvulopalatopharyngoplasty&lt;b&gt; &lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            VPAP - &lt;/b&gt;Variable positive airway pressure&lt;b&gt;&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            WAFA - &lt;/b&gt;Wake time after final awakening&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            &lt;b&gt;WASO - &lt;/b&gt;Wake time after sleep onset&lt;b&gt;&lt;br&gt;&lt;br /&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;            XPAP - &lt;/b&gt;Any type of positive airway pressure device&lt;/font&gt;&lt;font size="-1"&gt;&lt;b&gt;&lt;font face="Times"&gt;&lt;/font&gt;&lt;/b&gt;&lt;/font&gt;&lt;br&gt;&lt;br /&gt;            &lt;br&gt;&lt;br /&gt;          &lt;/p&gt;&lt;br /&gt;        &lt;/blockquote&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/8977896270362279183-5637621925649200802?l=insomniatherapycenter.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/5637621925649200802/comments/default' title='Poskan Komentar'/><link rel='replies' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/sleep-terms-definitions-and.html#comment-form' title='0 Komentar'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/5637621925649200802'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/5637621925649200802'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/sleep-terms-definitions-and.html' title='Sleep Terms, Definitions and Abbreviations'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><thr:total>0</thr:total></entry><entry><id>tag:blogger.com,1999:blog-8977896270362279183.post-6676960464710618577</id><published>2009-04-16T23:47:00.002-07:00</published><updated>2009-04-28T01:08:23.879-07:00</updated><title type='text'>Insomnia</title><content type='html'>&lt;b&gt;Insomnia&lt;/b&gt; is a symptom&lt;sup id="cite_ref-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;1&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; of a sleeping disorder characterized by persistent difficulty falling asleep or staying asleep despite the opportunity. Insomnia is a symptom, not a stand-alone diagnosis or a disease. By definition, insomnia is "difficulty initiating or maintaining sleep, or both" and it may be due to inadequate quality or quantity of sleep. It is typically followed by functional impairment while awake. Insomniacs have been known to complain about being unable to close their eyes or "rest their mind" for more than a few minutes at a time. Both organic and non-organic insomnia constitute a sleep disorder.&lt;sup id="cite_ref-WHO_1-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;2&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; &lt;p&gt;According to the U.S. &lt;span class="mw-redirect"&gt;Department of Health and Human Services&lt;/span&gt; in year 2007, approximately 64 million Americans suffer from insomnia on a regular basis each year.&lt;sup id="cite_ref-titleBrain_Basics:_Understanding_Sleep:_National_Institute_of_Neurological_Disorders_and_Stroke_.28NINDS.29_2-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;3&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Insomnia is 1.4 times more common in women than in men.&lt;sup id="cite_ref-3" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;table id="toc" class="toc" summary="Contents"&gt; &lt;tbody&gt;&lt;tr&gt; &lt;td&gt; &lt;div id="toctitle"&gt; &lt;h2&gt;Content:&lt;/h2&gt;  &lt;/div&gt; &lt;ul&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;1&lt;/span&gt; &lt;span class="toctext"&gt;Types of insomnia&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;2&lt;/span&gt; &lt;span class="toctext"&gt;Patterns of insomnia&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;3&lt;/span&gt; &lt;span class="toctext"&gt;Causes&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;4&lt;/span&gt; &lt;span class="toctext"&gt;Epidemiology&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;5&lt;/span&gt; &lt;span class="toctext"&gt;Diagnosis&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;6&lt;/span&gt; &lt;span class="toctext"&gt;Sleep duration and mortality&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;7&lt;/span&gt; &lt;span class="toctext"&gt;Insomnia versus poor sleep quality&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;8&lt;/span&gt; &lt;span class="toctext"&gt;Treatment for insomnia&lt;/span&gt; &lt;ul&gt;&lt;li class="toclevel-2"&gt;&lt;span class="tocnumber"&gt;8.1&lt;/span&gt; &lt;span class="toctext"&gt;Non-pharmacological strategies&lt;/span&gt; &lt;ul&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.1.1&lt;/span&gt; &lt;span class="toctext"&gt;Cognitive behavior therapy&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt; &lt;/li&gt;&lt;li class="toclevel-2"&gt;&lt;span class="tocnumber"&gt;8.2&lt;/span&gt; &lt;span class="toctext"&gt;Medications&lt;/span&gt; &lt;ul&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.1&lt;/span&gt; &lt;span class="toctext"&gt;Benzodiazepines&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.2&lt;/span&gt; &lt;span class="toctext"&gt;Non-benzodiazepines&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.3&lt;/span&gt; &lt;span class="toctext"&gt;Antidepressants&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.4&lt;/span&gt; &lt;span class="toctext"&gt;Melatonin and melatonin agonists&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.5&lt;/span&gt; &lt;span class="toctext"&gt;Antihistamines&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.6&lt;/span&gt; &lt;span class="toctext"&gt;Atypical antipsychotics&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-3"&gt;&lt;span class="tocnumber"&gt;8.2.7&lt;/span&gt; &lt;span class="toctext"&gt;Other substances&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt; &lt;/li&gt;&lt;li class="toclevel-2"&gt;&lt;span class="tocnumber"&gt;8.3&lt;/span&gt; &lt;span class="toctext"&gt;Sexual activity&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt; &lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;9&lt;/span&gt; &lt;span class="toctext"&gt;See also&lt;/span&gt;&lt;/li&gt;&lt;li class="toclevel-1"&gt;&lt;span class="tocnumber"&gt;10&lt;/span&gt; &lt;span class="toctext"&gt;References&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt; &lt;/td&gt; &lt;/tr&gt; &lt;/tbody&gt;&lt;/table&gt; &lt;script type="text/javascript"&gt; //&lt;![CDATA[  if (window.showTocToggle) { var tocShowText = "show"; var tocHideText = "hide"; showTocToggle(); }  //]]&gt; &lt;/script&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Types of insomnia&lt;/span&gt; &lt;/p&gt;  &lt;p&gt;Although there are several different degrees of insomnia, three types of insomnia have been clearly identified: transient, acute, and chronic.&lt;/p&gt; &lt;ol&gt;&lt;li&gt;&lt;b&gt;Transient insomnia&lt;/b&gt; lasts from days to weeks. It can be caused by another disorder, by changes in the sleep environment, by the timing of sleep, severe depression, or by stress. Its consequences - sleepiness and impaired psychomotor performance - are similar to those of sleep deprivation.&lt;sup id="cite_ref-Roth_4-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;5&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/li&gt;&lt;li&gt;&lt;b&gt;&lt;a title="Acute (medicine)"&gt;Acute&lt;/a&gt; insomnia&lt;/b&gt; is the inability to consistently sleep well for a period of between three weeks to six months.&lt;sup id="cite_ref-5" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;6&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/li&gt;&lt;li&gt;&lt;b&gt;&lt;a title="Chronic (medical)" class="mw-redirect"&gt;Chronic&lt;/a&gt; insomnia&lt;/b&gt; lasts for years at a time. It can be caused by another disorder, or it can be a primary disorder. Its effects can vary according to its causes. They might include sleepiness, muscular fatigue, hallucinations, and/or mental fatigue; but people with chronic insomnia often show increased alertness. Some people that live with this disorder see things as though they were happening in slow motion, whereas moving objects seem to blend together. Can cause double vision.&lt;sup id="cite_ref-Roth_4-1" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;5&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/li&gt;&lt;/ol&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Patterns of insomnia&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;The pattern of insomnia often is related to the etiology.&lt;sup id="cite_ref-6" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;7&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Insomnia affects 8 in 10 people.&lt;/p&gt; &lt;ol&gt;&lt;li&gt;Onset insomnia - difficulty falling asleep at the beginning of the night, often associated with anxiety disorders.&lt;/li&gt;&lt;li&gt;&lt;span class="mw-redirect"&gt;Middle-of-the-Night Insomnia&lt;/span&gt; - Insomnia characterized by difficulty returning to sleep after awakening in the middle of the night or waking too early in the morning. Also referred to as nocturnal awakenings. Encompasses middle and terminal insomnia.&lt;/li&gt;&lt;li&gt;Middle insomnia - waking during the middle of the night, difficulty maintaining sleep. Often associated with pain disorders or medical illness.&lt;/li&gt;&lt;li&gt;Terminal (or late) insomnia - early morning waking. Characteristic of &lt;span class="mw-redirect"&gt;clinical depression&lt;/span&gt;.&lt;/li&gt;&lt;/ol&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Causes&lt;/span&gt; &lt;/p&gt;  &lt;p&gt;Insomnia can be caused by:&lt;/p&gt; &lt;ul&gt;&lt;li&gt;Psychoactive drugs or stimulants, including certain &lt;span class="mw-redirect"&gt;medications&lt;/span&gt;, &lt;span class="mw-redirect"&gt;herbs&lt;/span&gt;, caffeine, cocaine, ephedrine, amphetamines, methylphenidate, &lt;span class="mw-redirect"&gt;MDMA&lt;/span&gt;, methamphetamine and modafinil&lt;/li&gt;&lt;li&gt;&lt;span class="mw-redirect"&gt;Fluoroquinolone&lt;/span&gt; antibiotic drugs, see &lt;span class="mw-redirect"&gt;Fluoroquinolone toxicity&lt;/span&gt;, associated with more severe and chronic types of insomnia &lt;sup id="cite_ref-7" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;8&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/li&gt;&lt;li&gt;Hormone shifts such as those that precede menstruation and those during menopause&lt;/li&gt;&lt;li&gt;Life problems like fear, &lt;span class="mw-redirect"&gt;stress&lt;/span&gt;, anxiety, emotional or mental tension, work problems, financial stress, unsatisfactory sex life&lt;/li&gt;&lt;li&gt;Mental disorders such as bipolar disorder, &lt;span class="mw-redirect"&gt;clinical depression&lt;/span&gt;, &lt;span class="mw-redirect"&gt;general anxiety disorder&lt;/span&gt;, &lt;span class="mw-redirect"&gt;post traumatic stress disorder&lt;/span&gt;, schizophrenia, or &lt;span class="mw-redirect"&gt;obsessive compulsive disorder&lt;/span&gt;.&lt;/li&gt;&lt;li&gt;Disturbances of the circadian rhythm, such as shift work and jet lag, can cause an inability to sleep at some times of the day and excessive sleepiness at other times of the day. Jet lag is seen in people who travel through multiple time zones, as the time relative to the rising and setting of the sun no longer coincides with the body's internal concept of it. The insomnia experienced by shift workers is also a circadian rhythm sleep disorder.&lt;/li&gt;&lt;li&gt;Estrogen is considered to play a significant role in women’s mental health (including insomnia). A conceptual model of how estrogen affects mood was suggested by Douma et al 2005 based on their extensive literature review relating activity of endogenous, bio-identical and synthetic estrogen with mood and well-being. They concluded the sudden estrogen withdrawal, fluctuating estrogen, and periods of sustained estrogen low levels correlated with significant mood lowering. Clinical recovery from depression postpartum, perimenopause, and postmenopause was shown to be effective after levels of estrogen were stabilized and/or restored.&lt;sup id="cite_ref-pmid16292022_8-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;9&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-pmid17909167_9-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;10&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/li&gt;&lt;li&gt;Certain neurological disorders, brain lesions, or a history of traumatic brain injury&lt;/li&gt;&lt;li&gt;Medical conditions such as hyperthyroidism&lt;/li&gt;&lt;li&gt;Abuse of over-the counter or prescription sleep aids can produce &lt;span class="mw-redirect"&gt;rebound insomnia&lt;/span&gt;&lt;/li&gt;&lt;li&gt;Poor sleep hygiene, e.g., noise&lt;/li&gt;&lt;li&gt;Parasomnia, which includes a number of disruptive sleep events including nightmares, sleepwalking, violent behavior while sleeping, and REM behavior disorder, in which a person moves his/her physical body in response to events within his/her dreams&lt;/li&gt;&lt;li&gt;A rare genetic condition can cause a prion-based, permanent and eventually fatal form of insomnia called fatal familial insomnia&lt;/li&gt;&lt;li&gt;&lt;span class="mw-redirect"&gt;Parasites&lt;/span&gt; can cause intestinal disturbances while sleeping.&lt;/li&gt;&lt;/ul&gt; &lt;p&gt;A common misperception is that the amount of sleep a person requires decreases as he or she ages. The ability to sleep for long periods, rather than the need for sleep, appears to be lost as people get older. Some elderly insomniacs toss and turn in bed and occasionally fall off the bed at night, diminishing the amount of sleep they receive.&lt;sup id="cite_ref-10" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;11&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;An overactive mind or physical pain may also be causes. Finding the underlying cause of insomnia is usually necessary to cure it. Insomnia can be common after the loss of a loved one, even years or decades after the death, if they have not gone through the grieving process. Overall, symptoms and the degree of their severity affect each individual differently depending on their mental health, physical condition, and attitude or personality.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Epidemiology&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;The National Sleep Foundation's 2002 &lt;i&gt;Sleep in America&lt;/i&gt; poll showed that 58% of adults in the U.S. experienced symptoms of insomnia a few nights a week or more.&lt;sup id="cite_ref-sleepfoundation_11-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;12&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Although insomnia was the most common sleep problem among about one half of older adults (48%), they were less likely to experience frequent symptoms of insomnia than their younger counterparts (45% vs. 62%), and their symptoms were more likely to be associated with medical conditions, according to the 2003 poll of adults between the ages of 55 and 84.&lt;sup id="cite_ref-sleepfoundation_11-1" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;12&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Diagnosis&lt;/span&gt; &lt;/p&gt;  &lt;p&gt;Specialists in sleep medicine are qualified to diagnose the many different sleep disorders. Patients with various disorders including delayed sleep phase syndrome are often mis-diagnosed with insomnia. If a patient has trouble getting to sleep, but has normal sleep pattern once asleep, a circadian rhythm disorder is a likely cause.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Sleep duration and mortality&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;A survey of 1.1 million residents in America found that those who reported sleeping 7.5 hours or more had an increased rate of mortality whereas those who slept 6 hours or less had a reduced mortality ratio. Getting 8.5 or more hours of sleep per night increases the mortality rate by 15%. Severe insomnia - sleeping less than 3.5 hours in women and 4.5 hours in men - leads to a 15% increase in mortality. However, most of the increase in mortality from severe insomnia was discounted after controlling for comorbid disorders. After controlling for sleep duration and insomnia, use of sleeping pills was also found to be associated with an increased mortality rate. The lowest mortality was seen in individuals who slept between six and a half and seven and a half hours per night. Even sleeping only 4.5 hours per night is associated with very little increase in mortality. Thus mild to moderate insomnia for most people may actually increase longevity and severe insomnia has only a very small effect on mortality. As long as a patient refrains from using sleeping pills there is little to no increase in mortality associated with insomnia but there does appear to be an increase in longevity. This is reassuring for patients with insomnia in that despite the sometimes unpleasantness of insomnia, insomnia itself appears to be associated with increased longevity. It is unclear why sleeping longer than 7.5 hours is associated with excess mortality.&lt;sup id="cite_ref-12" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;13&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Insomnia versus poor sleep quality&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;Poor sleep quality can occur as a result of sleep apnea or &lt;span class="mw-redirect"&gt;clinical depression&lt;/span&gt;. Poor sleep quality is caused by the individual not reaching stage 4 or delta sleep which has restorative properties. There are, however, people who are unable to achieve stage 4 sleep due to brain damage who lead perfectly normal lives.&lt;/p&gt; &lt;p&gt;Sleep apnea is a condition that occurs when a sleeping person's breathing is interrupted, thus interrupting the normal sleep cycle. With the obstructive form of the condition, some part of the sleeper's respiratory tract loses muscle tone and partially collapses. People with obstructive sleep apnea often do not remember awakening or having difficulty breathing, but they complain of excessive sleepiness during the day. Central sleep apnea interrupts the normal breathing stimulus of the central nervous system, and the individual must actually wake up to resume breathing. This form of apnea is often related to a cerebral vascular condition, congestive heart failure, and premature aging.&lt;/p&gt; &lt;p&gt;Major depression leads to alterations in the function of the hypothalamic-pituitary-adrenal axis, causing excessive release of cortisol which can lead to poor sleep quality.&lt;/p&gt; &lt;p&gt;Nocturnal polyuria, excessive nighttime urination, can be very disturbing to sleep.&lt;sup id="cite_ref-13" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;14&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Treatment for insomnia&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;In many cases, insomnia is caused by another disease, side effects from medications or a psychological problem. It is important to identify or rule out medical and psychological before deciding on the treatment for the insomnia.&lt;sup id="cite_ref-14" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;15&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Attention to sleep hygiene is an important first line treatment strategy and should be tried before any pharmacological approach is considered.&lt;sup id="cite_ref-15" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;16&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Non-pharmacological strategies&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;Non-pharmacological strategies are superior to hypnotic medication for insomnia because tolerance develops to the hypnotic effects as well as &lt;span class="mw-redirect"&gt;dependence&lt;/span&gt; can develop with &lt;span class="mw-redirect"&gt;rebound withdrawal effects&lt;/span&gt; developing upon discontinuation. Hypnotic medication is therefore only recommended for short term use. Non pharmacological strategies however, have long lasting improvements to insomnia and are recommended as a first line and long term strategy of managing insomnia. The strategies include attention to sleep hygiene, stimulus control, behavioral interventions, sleep-restriction therapy, patient education and relaxation therapy.&lt;sup id="cite_ref-16" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;17&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Cognitive behavior therapy&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;A recent study found that &lt;span class="mw-redirect"&gt;cognitive behavior therapy&lt;/span&gt; is more effective than hypnotic medications in controlling insomnia. In this therapy, patients are taught improved sleep habits and relieved of counter-productive assumptions about sleep. Hypnotic medications are equally effective in the short term treatment of insomnia but their effects wear off over time due to tolerance. The effects of &lt;span class="mw-redirect"&gt;cognitive behavior therapy&lt;/span&gt; have sustained and lasting effects on treating insomnia long after therapy has been discontinued.&lt;sup id="cite_ref-JacobsG2004Cognitive_17-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;18&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-18" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;19&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; The addition of hypnotic medications with CBT adds no benefit in insomnia. The long lasting benefits of a course of CBT shows superiority over pharmacological hypnotic drugs. Even in the short term when compared to short term hypnotic medication such as zolpidem (&lt;span class="mw-redirect"&gt;Ambien&lt;/span&gt;), CBT still shows significant superiority. Thus CBT is recommended as a first line treatment for insomnia.&lt;sup id="cite_ref-19" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;20&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Medications&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;Many insomniacs rely on &lt;span class="mw-redirect"&gt;sleeping tablets&lt;/span&gt; and other sedatives to get rest. All sedative drugs have the potential of causing &lt;span class="mw-redirect"&gt;psychological dependence&lt;/span&gt; where the individual cannot psychologically accept that they can sleep without drugs&lt;sup class="noprint Template-Fact"&gt;&lt;span title="This claim needs references to reliable sources since March 2009" style="white-space: nowrap;"&gt;[&lt;/span&gt;&lt;/sup&gt;&lt;sup class="noprint Template-Fact"&gt;&lt;span title="This claim needs references to reliable sources since March 2009" style="white-space: nowrap;"&gt;&lt;i&gt;&lt;a title="Wikipedia:Citation needed"&gt;citation needed&lt;/a&gt;&lt;/i&gt;]&lt;/span&gt;&lt;/sup&gt;. Certain classes of sedatives such as benzodiazepines and newer nonbenzodiazepine drugs can also cause physical dependence which manifests in withdrawal symptoms if the drug is not carefully titrated down. The benzodiazepine and nonbenzodiazepine hypnotic medications also have a number of side effects such as day time fatigue, motor vehicle crashes, cognitive impairments and falls and fractures. Elderly people are more sensitive to these side effects.&lt;sup id="cite_ref-20" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;21&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;In comparing the options, a systematic review found that benzodiazepines and nonbenzodiazepines have similar efficacy which was not significantly more than for antidepressants.&lt;sup id="cite_ref-pmid17619935_21-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;22&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Benzodiazepines did not have a significant tendency for more adverse drug reactions.&lt;sup id="cite_ref-pmid17619935_21-1" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;22&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Chronic users of hypnotic medications for insomnia do not have better sleep than chronic insomniacs who do not take medications. In fact, chronic users of hypnotic medications actually have more regular nighttime awakenings than insomniacs who do not take hypnotic medications.&lt;sup id="cite_ref-22" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;23&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; A further review of the literature regarding benzodiazepine hypnotic as well as the nonbenzodiazepines concluded that these drugs caused an unjustifiable risk to the individual and to public health and lack evidence of long term effectiveness. The risks include &lt;span class="mw-redirect"&gt;dependence&lt;/span&gt;, accidents and other adverse effects. Gradual discontinuation of hypnotics in long term users leads to improved health without worsening of sleep. Preferably hypnotics should be prescribed for only a few days at the lowest effective dose and avoided altogether wherever possible in the elderly.&lt;sup id="cite_ref-23" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;24&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Benzodiazepines&lt;/span&gt;&lt;/p&gt;  &lt;div class="rellink noprint relarticle mainarticle"&gt;Main article: Benzodiazepine&lt;/div&gt; &lt;p&gt;The most commonly used class of hypnotics prescribed for insomnia are the benzodiazepines. Benzodiazepines bind unselectively to the GABA&lt;sub&gt;A&lt;/sub&gt; receptor.&lt;sup id="cite_ref-pmid17619935_21-2" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;22&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; These include drugs such as temazepam, flunitrazepam, triazolam, flurazepam, midazolam, nitrazepam and quazepam. These drugs can lead to tolerance, physical dependence and the benzodiazepine withdrawal syndrome upon discontinuation, especially after consistent usage over long periods of time. Benzodiazepines while inducing unconsciousness, actually worsen sleep as they promote light sleep whilst decreasing time spent in deep sleep such as &lt;span class="mw-redirect"&gt;REM sleep&lt;/span&gt;.&lt;sup id="cite_ref-24" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;25&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; A further problem is with regular use of short acting sleep aids for insomnia, day time &lt;span class="mw-redirect"&gt;rebound anxiety&lt;/span&gt; can emerge.&lt;sup id="cite_ref-25" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;26&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Non-benzodiazepines&lt;/span&gt;&lt;/p&gt;  &lt;div class="rellink noprint relarticle mainarticle"&gt;Main article: Nonbenzodiazepine&lt;/div&gt; &lt;p&gt;Nonbenzodiazepine sedative-hypnotic drugs, such as zolpidem, zaleplon, zopiclone and eszopiclone, are a newer classification of hypnotic medications. They work on the benzodiazepine site on the GABA&lt;sub&gt;A&lt;/sub&gt; receptor complex similarly to the benzodiazepine class of drugs. Some but not all of the nonbenzodiazepines are selective for the α&lt;sub&gt;1&lt;/sub&gt; subunit on GABA&lt;sub&gt;A&lt;/sub&gt; receptors which is responsible for inducing sleep and may therefore have a cleaner side effect profile than the older benzodiazepines. Zopiclone and eszopiclone like benzodiazepine drugs bind unselectively to α&lt;sub&gt;1&lt;/sub&gt;, α&lt;sub&gt;2&lt;/sub&gt;, α&lt;sub&gt;3&lt;/sub&gt; and α&lt;sub&gt;5&lt;/sub&gt; GABA&lt;sub&gt;A&lt;/sub&gt; &lt;span class="mw-redirect"&gt;benzodiazepine receptors&lt;/span&gt;.&lt;sup id="cite_ref-26" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;27&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Zolpidem is more selective and zaleplon is highly selective for the α&lt;sub&gt;1&lt;/sub&gt; subunit thus giving them an advantage over benzodiazepines in terms of &lt;span class="mw-redirect"&gt;sleep architecture&lt;/span&gt; and a reduction in side effects.&lt;sup id="cite_ref-27" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;28&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-28" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;29&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; However, there are controversies over whether these non-benzodiazepine drugs are superior to benzodiazepines. These drugs appear to cause both psychological dependence and physical dependence though less than traditional benzodiazepines and can also cause the same memory and cognitive disturbances along with morning sedation.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Antidepressants&lt;/span&gt;&lt;/p&gt;  &lt;div class="rellink noprint relarticle mainarticle"&gt;Main article: &lt;span class="mw-redirect"&gt;Antidepressants&lt;/span&gt;&lt;/div&gt; &lt;p&gt;Some antidepressants such as amitriptyline, doxepin, mirtazapine, and trazodone can often have a very strong sedative effect, and are prescribed &lt;span class="mw-redirect"&gt;off label&lt;/span&gt; to treat insomnia. &lt;sup id="cite_ref-29" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;30&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; The major drawback of these drugs is that they have &lt;span class="mw-redirect"&gt;antihistaminergic&lt;/span&gt;, anticholinergic and &lt;span class="mw-redirect"&gt;antiadrenergic&lt;/span&gt; properties which can lead to many side effects. Some also alter &lt;span class="mw-redirect"&gt;sleep architecture&lt;/span&gt;. As with many benzodiazepines, the use of antidepressants in the treatment of insomnia can lead to physical dependence; withdrawal may induce &lt;span class="mw-redirect"&gt;rebound insomnia&lt;/span&gt; and actually further complicate matters in the long-term.&lt;/p&gt; &lt;p&gt;Mirtazapine is known to decrease sleep latency, promoting sleep effiency and increasing the total amount of sleeping time in patients suffering from both depression and insomnia &lt;sup id="cite_ref-30" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;31&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; &lt;sup id="cite_ref-31" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;32&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Melatonin and melatonin agonists&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;The hormone and supplement melatonin is effective in several types of insomnia. Melatonin has demonstrated effectiveness equivalent to the prescription sleeping tablet zopiclone in inducing sleep and regulating the sleep/waking cycle.&lt;sup id="cite_ref-32" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;33&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; One particular benefit of melatonin is that it can treat insomnia without altering the &lt;span class="mw-redirect"&gt;sleep pattern&lt;/span&gt; which is altered by many prescription sleeping tablets. Another benefit is it does not impair performance related skills.&lt;sup id="cite_ref-33" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;34&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-34" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;35&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;Melatonin agonists, including ramelteon (Rozerem) and tasimelteon, seem to lack the potential for abuse and dependence. This class of drugs has a relatively mild side effect profile and lower likelihood of causing morning sedation. While these drugs show good effects for the treatment of insomnia due to jet lag,&lt;sup id="cite_ref-35" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;36&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; the results for other forms of insomnia are less promising.&lt;sup id="cite_ref-pmid17803013_36-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;37&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;Natural substances such as &lt;span class="mw-redirect"&gt;5-HTP&lt;/span&gt; and L-Tryptophan have been said to fortify the serotonin-melatonin pathway and aid people with various sleep disorders including insomnia.&lt;sup id="cite_ref-37" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;38&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Antihistamines&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;The &lt;span class="mw-redirect"&gt;antihistamine&lt;/span&gt; diphenhydramine is widely used in nonprescription sleep aids such as Tylenol PM®, with a 50 mg recommended dose mandated by the FDA. In the United Kingdom, Australia, New Zealand, South Africa, and other countries, a 25 mg to 50 mg recommended dose is permitted. While it is available over the counter, the effectiveness of these agents may decrease over time and the incidence of next-day sedation is higher than for most of the newer prescription drugs. Dependence does not seem to be an issue with this class of drugs.&lt;/p&gt; &lt;p&gt;Cyproheptadine is a useful alternative to benzodiazepine hypnotics in the treatment of insomnia. Cyproheptadine may be superior to benzodiazepines in the treatment of insomnia because cyproheptadine enhances sleep quality and quantity whereas benzodiazepines tend to decrease sleep quality.&lt;sup id="cite_ref-38" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;39&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Atypical antipsychotics&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;Low doses of certain &lt;span class="mw-redirect"&gt;atypical antipsychotics&lt;/span&gt; such as quetiapine, olanzapine and risperidone are also prescribed for their sedative effect but the danger of neurological and cognitive side effects make these drugs a poor choice to treat insomnia. Over time, quetiapine may lose its effectiveness as a sedative. The ability of quetiapine to produce sedation is determined by the dosage. Higher doses (300 mg - 900 mg) are usually taken for its use as an antipsychotic, while lower doses (25 mg - 200 mg) have a marked sedative effect, e.g. if a patient takes 300 mg, he/she will more likely benefit from the drug's antipsychotic effects, but if the dose is brought down to 100 mg, it will leave the patient feeling more sedated than at 300 mg, because it primarily works as a sedative at lower doses.&lt;/p&gt; &lt;p&gt;Eplivanserin is an investigational drug with a mechanism similar to these antipsychotics, but probably with less side effects.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Other substances&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;Some insomniacs use herbs such as &lt;span class="mw-redirect"&gt;valerian&lt;/span&gt;, chamomile, lavender, hops, and &lt;span class="mw-redirect"&gt;passion-flower&lt;/span&gt;. Valerian has undergone multiple studies and appears to be modestly effective.&lt;sup id="cite_ref-pmid10761819_39-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;40&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-pmid16335333_40-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;41&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;sup id="cite_ref-pmid17561634_41-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;42&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt; Cannabis has also been proven as an effective treatment for insomnia. &lt;sup id="cite_ref-42" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;43&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;&lt;span class="mw-redirect"&gt;Middle-of-the-night awakenings&lt;/span&gt; due to polyuria or other effects from alcohol consumption are common, and hangovers can also lead to morning grogginess.&lt;/p&gt; &lt;p&gt;Insomnia may be a symptom of magnesium deficiency, or low magnesium levels, but this has not yet been proven. A healthy diet containing magnesium, can help to improve sleep in individuals without an adequate intake of magnesium.&lt;sup id="cite_ref-pmid9703590_43-0" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;44&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;Other reports cite the use of an elixir of cider vinegar and honey but the evidence for this is only anecdotal.&lt;sup id="cite_ref-44" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;45&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;&lt;/p&gt; &lt;p&gt;Another reported effective natural treatment of insomnia is the use of the amino acids L-Tryptophan or 5-HTTP (not both at the same time) thirty minutes prior to sleeping. These amino acids serve to aid your body and brain in the production of Serotonin and Melatonin, both essential for proper sleep &lt;sup id="cite_ref-45" class="reference"&gt;&lt;a title=""&gt;&lt;span&gt;[&lt;/span&gt;46&lt;span&gt;]&lt;/span&gt;&lt;/a&gt;&lt;/sup&gt;. These must be taken on an empty stomach for proper absorption. If the amino acids alone are insufficient at treating the insomnia, then you may suffer from a blood-sugar related issue such as hypoglycemia or hyperglycemia. In this case, people have reported that taking Chromium/Vanadium together with Alpha Lipoic Acid - both of which aid in balancing blood sugar - fifteen minutes after taking the amino acids seems to be fairly effective.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;Sexual activity&lt;/span&gt;&lt;/p&gt;  &lt;p&gt;In several cases, sexual intercourse has been found to heavily reduce stress patterns. Although in many cases stress is not the cause of insomnia.&lt;/p&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;See also&lt;/span&gt;&lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Sleep&lt;/li&gt;&lt;li&gt;Sleep disorder&lt;/li&gt;&lt;li&gt;Fatal familial insomnia&lt;/li&gt;&lt;li&gt;Sleep deprivation&lt;/li&gt;&lt;li&gt;Delayed sleep phase syndrome&lt;/li&gt;&lt;li&gt;Actigraphy&lt;/li&gt;&lt;li&gt;Thai Ngoc&lt;/li&gt;&lt;/ul&gt; &lt;p&gt;&lt;span class="mw-headline"&gt;References&lt;/span&gt;&lt;/p&gt;  &lt;div class="references-small"&gt; &lt;ol class="references"&gt;&lt;li id="cite_note-0"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web" id="CITEREFRowleyNicholas_Lorenzo2005"&gt;Rowley, James A.; Nicholas Lorenzo (September 7, 2005). &lt;a class="external text" title="http://www.emedicine.com/neuro/TOPIC418.HTM#target10" rel="nofollow"&gt;"Insomnia"&lt;/a&gt;. eMedicine from WebMD&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.emedicine.com/neuro/TOPIC418.HTM#target10" rel="nofollow"&gt;http://www.emedicine.com/neuro/TOPIC418.HTM#target10&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2008-08-04&lt;/span&gt;.  "That insomnia is a symptom, not a disease, is important to note; ..."&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Insomnia&amp;amp;rft.atitle=&amp;amp;rft.aulast=Rowley&amp;amp;rft.aufirst=James+A.&amp;amp;rft.au=Rowley%2C+James+A.&amp;amp;rft.au=Nicholas+Lorenzo&amp;amp;rft.date=September+7%2C+2005&amp;amp;rft.pub=eMedicine+from+WebMD&amp;amp;rft_id=http%3A%2F%2Fwww.emedicine.com%2Fneuro%2FTOPIC418.HTM%23target10&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-WHO-1"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://www.euro.who.int/document/E84683_1.pdf" rel="nofollow"&gt;"WHO technical meeting on sleep and health"&lt;/a&gt; (pdf)&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.euro.who.int/document/E84683_1.pdf" rel="nofollow"&gt;http://www.euro.who.int/document/E84683_1.pdf&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2009-01-25&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=WHO+technical+meeting+on+sleep+and+health&amp;amp;rft.atitle=&amp;amp;rft_id=http%3A%2F%2Fwww.euro.who.int%2Fdocument%2FE84683_1.pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://www.who.int/selection_medicines/committees/expert/17/application/Section24_GAD.pdf" rel="nofollow"&gt;"Dyssomnias"&lt;/a&gt; (pdf). WHO. 7-11&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.who.int/selection_medicines/committees/expert/17/application/Section24_GAD.pdf" rel="nofollow"&gt;http://www.who.int/selection_medicines/committees/expert/17/application/Section24_GAD.pdf&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2009-01-25&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Dyssomnias&amp;amp;rft.atitle=&amp;amp;rft.pages=7-11&amp;amp;rft.pub=WHO&amp;amp;rft_id=http%3A%2F%2Fwww.who.int%2Fselection_medicines%2Fcommittees%2Fexpert%2F17%2Fapplication%2FSection24_GAD.pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-titleBrain_Basics:_Understanding_Sleep:_National_Institute_of_Neurological_Disorders_and_Stroke_.28NINDS.29-2"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://www.ninds.nih.gov/disorders/brain_basics/understanding_sleep.htm" rel="nofollow"&gt;"Brain Basics: Understanding Sleep: National Institute of Neurological Disorders and Stroke (NINDS)"&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.ninds.nih.gov/disorders/brain_basics/understanding_sleep.htm" rel="nofollow"&gt;http://www.ninds.nih.gov/disorders/brain_basics/understanding_sleep.htm&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2007-12-16&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Brain+Basics%3A+Understanding+Sleep%3A+National+Institute+of+Neurological+Disorders+and+Stroke+%28NINDS%29&amp;amp;rft.atitle=&amp;amp;rft_id=http%3A%2F%2Fwww.ninds.nih.gov%2Fdisorders%2Fbrain_basics%2Funderstanding_sleep.htm&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-3"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://pn.psychiatryonline.org/cgi/content/full/42/10/40" rel="nofollow"&gt;"Several Sleep Disorders Reflect Gender Differences"&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://pn.psychiatryonline.org/cgi/content/full/42/10/40" rel="nofollow"&gt;http://pn.psychiatryonline.org/cgi/content/full/42/10/40&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2008-09-05&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Several+Sleep+Disorders+Reflect+Gender+Differences&amp;amp;rft.atitle=&amp;amp;rft_id=http%3A%2F%2Fpn.psychiatryonline.org%2Fcgi%2Fcontent%2Ffull%2F42%2F10%2F40&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-Roth-4"&gt;^ &lt;sup&gt;&lt;i&gt;&lt;b&gt;a&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;sup&gt;&lt;i&gt;&lt;b&gt;b&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFRothTimothy_Roehrs2004"&gt;Roth, Thomas; Timothy Roehrs (2004-02-25). "Insomnia: Epidemiology, characteristics, and consequences". &lt;i&gt;Clinical Cornerstone&lt;/i&gt; &lt;b&gt;5&lt;/b&gt; (3): 5–15. &lt;/cite&gt;&lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1016%2FS1098-3597%2803%2990031-7" rel="nofollow"&gt;10.1016/S1098-3597(03)90031-7&lt;/a&gt;&lt;/span&gt;.&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Insomnia%3A+Epidemiology%2C+characteristics%2C+and+consequences&amp;amp;rft.jtitle=Clinical+Cornerstone&amp;amp;rft.aulast=Roth&amp;amp;rft.aufirst=Thomas&amp;amp;rft.au=Roth%2C+Thomas&amp;amp;rft.au=Timothy+Roehrs&amp;amp;rft.date=2004-02-25&amp;amp;rft.volume=5&amp;amp;rft.issue=3&amp;amp;rft.pages=5%E2%80%9315&amp;amp;rft_id=info:doi/10.1016%2FS1098-3597%2803%2990031-7&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-5"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://articles.directorym.com/Insomnia-a352.html" rel="nofollow"&gt;"Insomnia - sleeplessness, chronic insomnia, acute insomnia, mental ..."&lt;/a&gt;. driectoryM articles&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://articles.directorym.com/Insomnia-a352.html" rel="nofollow"&gt;http://articles.directorym.com/Insomnia-a352.html&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2008-04-29&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Insomnia+-+sleeplessness%2C+chronic+insomnia%2C+acute+insomnia%2C+mental+...&amp;amp;rft.atitle=&amp;amp;rft.pub=driectoryM+articles&amp;amp;rft_id=http%3A%2F%2Farticles.directorym.com%2FInsomnia-a352.html&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-6"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;span class="external text"&gt;eMedicine - Sleep Disorders : Article by Curley L Bonds, MD&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-7"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFLawrence_KR.2C_Adra_M.2C_Keir_C2006"&gt;Lawrence KR, Adra M, Keir C (June 2006). "Hypoglycemia-induced anoxic brain injury possibly associated with levofloxacin". &lt;i&gt;J. Infect.&lt;/i&gt; &lt;b&gt;52&lt;/b&gt; (6): e177–80. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1016%2Fj.jinf.2005.08.024" rel="nofollow"&gt;10.1016/j.jinf.2005.08.024&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/16269178"&gt;PMID 16269178&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Hypoglycemia-induced+anoxic+brain+injury+possibly+associated+with+levofloxacin&amp;amp;rft.jtitle=J.+Infect.&amp;amp;rft.aulast=Lawrence+KR%2C+Adra+M%2C+Keir+C&amp;amp;rft.au=Lawrence+KR%2C+Adra+M%2C+Keir+C&amp;amp;rft.date=June+2006&amp;amp;rft.volume=52&amp;amp;rft.issue=6&amp;amp;rft.pages=e177%E2%80%9380&amp;amp;rft_id=info:doi/10.1016%2Fj.jinf.2005.08.024&amp;amp;rft_id=info:pmid/16269178&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid16292022-8"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFDouma.2C_S.L.2C_Husband.2C_C..2C_O.E2.80.99Donnell.2C_M.E..2C_Barwin.2C_B.N..2C_Woodend_A.K.2005"&gt;Douma, S.L, Husband, C., O’Donnell, M.E., Barwin, B.N., Woodend A.K. (2005). "Estrogen-related Mood Disorders Reproductive Life Cycle Factors". &lt;i&gt;Advances in Nursing Science&lt;/i&gt; &lt;b&gt;28&lt;/b&gt; (4): 364–375. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/16292022"&gt;PMID 16292022&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Estrogen-related+Mood+Disorders+Reproductive+Life+Cycle+Factors&amp;amp;rft.jtitle=Advances+in+Nursing+Science&amp;amp;rft.aulast=Douma%2C+S.L%2C+Husband%2C+C.%2C+O%E2%80%99Donnell%2C+M.E.%2C+Barwin%2C+B.N.%2C+Woodend+A.K.&amp;amp;rft.au=Douma%2C+S.L%2C+Husband%2C+C.%2C+O%E2%80%99Donnell%2C+M.E.%2C+Barwin%2C+B.N.%2C+Woodend+A.K.&amp;amp;rft.date=2005&amp;amp;rft.volume=28&amp;amp;rft.issue=4&amp;amp;rft.pages=364%E2%80%93375&amp;amp;rft_id=info:pmid/16292022&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid17909167-9"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFLasiuk.2C_GC_and_Hegadoren.2C_KM2007"&gt;Lasiuk, GC and Hegadoren, KM (2007). "The Effects of Estradiol on Central Serotonergic Systems and Its Relationship to Mood in Women". &lt;i&gt;Biological Research for Nursing (2007),&lt;/i&gt; &lt;b&gt;9&lt;/b&gt; (2): 147–160. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1177%2F1099800407305600" rel="nofollow"&gt;10.1177/1099800407305600&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/17909167"&gt;PMID 17909167&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=The+Effects+of+Estradiol+on+Central+Serotonergic+Systems+and+Its+Relationship+to+Mood+in+Women&amp;amp;rft.jtitle=Biological+Research+for+Nursing+%282007%29%2C&amp;amp;rft.aulast=Lasiuk%2C+GC+and+Hegadoren%2C+KM&amp;amp;rft.au=Lasiuk%2C+GC+and+Hegadoren%2C+KM&amp;amp;rft.date=2007&amp;amp;rft.volume=9&amp;amp;rft.issue=2&amp;amp;rft.pages=147%E2%80%93160&amp;amp;rft_id=info:doi/10.1177%2F1099800407305600&amp;amp;rft_id=info:pmid/17909167&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-10"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;span class="external text"&gt;American Family Physician: Chronic Insomnia: A Practical Review&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-sleepfoundation-11"&gt;^ &lt;sup&gt;&lt;i&gt;&lt;b&gt;a&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;sup&gt;&lt;i&gt;&lt;b&gt;b&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;/cite&gt;&lt;a class="external text" title="http://www.sleepfoundation.org/site/c.huIXKjM0IxF/b.2417355/k.143E/2002_Sleep_in_America_Poll.htm" rel="nofollow"&gt;"2002 Sleep in America Poll"&lt;/a&gt;. National Sleep Foundation&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.sleepfoundation.org/site/c.huIXKjM0IxF/b.2417355/k.143E/2002_Sleep_in_America_Poll.htm" rel="nofollow"&gt;http://www.sleepfoundation.org/site/c.huIXKjM0IxF/b.2417355/k.143E/2002_Sleep_in_America_Poll.htm&lt;/a&gt;&lt;/span&gt;&lt;span class="reference-accessdate"&gt;. Retrieved on 2008-08-13&lt;/span&gt;.&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=2002+Sleep+in+America+Poll&amp;amp;rft.atitle=&amp;amp;rft.pub=National+Sleep+Foundation&amp;amp;rft_id=http%3A%2F%2Fwww.sleepfoundation.org%2Fsite%2Fc.huIXKjM0IxF%2Fb.2417355%2Fk.143E%2F2002_Sleep_in_America_Poll.htm&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-12"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFKripke_DF.2C_Garfinkel_L.2C_Wingard_DL.2C_Klauber_MR.2C_Marler_MR2002"&gt;Kripke DF, Garfinkel L, Wingard DL, Klauber MR, Marler MR (February 2002). "&lt;a class="external text" title="http://archpsyc.ama-assn.org/cgi/content/full/59/2/131" rel="nofollow"&gt;Mortality associated with sleep duration and insomnia&lt;/a&gt;". &lt;i&gt;Arch. Gen. Psychiatry&lt;/i&gt; &lt;b&gt;59&lt;/b&gt; (2): 131–6. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/11825133"&gt;PMID 11825133&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://archpsyc.ama-assn.org/cgi/content/full/59/2/131" rel="nofollow"&gt;http://archpsyc.ama-assn.org/cgi/content/full/59/2/131&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Mortality+associated+with+sleep+duration+and+insomnia&amp;amp;rft.jtitle=Arch.+Gen.+Psychiatry&amp;amp;rft.aulast=Kripke+DF%2C+Garfinkel+L%2C+Wingard+DL%2C+Klauber+MR%2C+Marler+MR&amp;amp;rft.au=Kripke+DF%2C+Garfinkel+L%2C+Wingard+DL%2C+Klauber+MR%2C+Marler+MR&amp;amp;rft.date=February+2002&amp;amp;rft.volume=59&amp;amp;rft.issue=2&amp;amp;rft.pages=131%E2%80%936&amp;amp;rft_id=info:pmid/11825133&amp;amp;rft_id=http%3A%2F%2Farchpsyc.ama-assn.org%2Fcgi%2Fcontent%2Ffull%2F59%2F2%2F131&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-13"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="book"&gt;&lt;i&gt;&lt;a class="external text" title="http://www.neurology.org/cgi/content/full/64/12_suppl_3/S12" rel="nofollow"&gt;Sleep issues in Parkinson’s disease&lt;/a&gt;&lt;/i&gt;. Neurology. 2005. pp. 64; S12–20&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.neurology.org/cgi/content/full/64/12_suppl_3/S12" rel="nofollow"&gt;http://www.neurology.org/cgi/content/full/64/12_suppl_3/S12&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=book&amp;amp;rft.btitle=Sleep+issues+in+Parkinson%E2%80%99s+disease&amp;amp;rft.au=Adler+and+Thorpy&amp;amp;rft.date=2005&amp;amp;rft.pages=pp.%26nbsp%3B64%3B+S12%E2%80%9320&amp;amp;rft.pub=Neurology&amp;amp;rft_id=http%3A%2F%2Fwww.neurology.org%2Fcgi%2Fcontent%2Ffull%2F64%2F12_suppl_3%2FS12&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-14"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFWortelboer_U.2C_Cohrs_S.2C_Rodenbeck_A.2C_R.C3.BCther_E2002"&gt;Wortelboer U, Cohrs S, Rodenbeck A, Rüther E (2002). "Tolerability of hypnosedatives in older patients". &lt;i&gt;Drugs Aging&lt;/i&gt; &lt;b&gt;19&lt;/b&gt; (7): 529–39. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.2165%2F00002512-200219070-00006" rel="nofollow"&gt;10.2165/00002512-200219070-00006&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/12182689"&gt;PMID 12182689&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Tolerability+of+hypnosedatives+in+older+patients&amp;amp;rft.jtitle=Drugs+Aging&amp;amp;rft.aulast=Wortelboer+U%2C+Cohrs+S%2C+Rodenbeck+A%2C+R%C3%BCther+E&amp;amp;rft.au=Wortelboer+U%2C+Cohrs+S%2C+Rodenbeck+A%2C+R%C3%BCther+E&amp;amp;rft.date=2002&amp;amp;rft.volume=19&amp;amp;rft.issue=7&amp;amp;rft.pages=529%E2%80%9339&amp;amp;rft_id=info:doi/10.2165%2F00002512-200219070-00006&amp;amp;rft_id=info:pmid/12182689&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-15"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFFlamer_HE1995"&gt;Flamer HE (June 1995). "Sleep problems". &lt;i&gt;Med. J. Aust.&lt;/i&gt; &lt;b&gt;162&lt;/b&gt; (11): 603–7. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/7791648"&gt;PMID 7791648&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Sleep+problems&amp;amp;rft.jtitle=Med.+J.+Aust.&amp;amp;rft.aulast=Flamer+HE&amp;amp;rft.au=Flamer+HE&amp;amp;rft.date=June+1995&amp;amp;rft.volume=162&amp;amp;rft.issue=11&amp;amp;rft.pages=603%E2%80%937&amp;amp;rft_id=info:pmid/7791648&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-16"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFKirkwood_CK1999"&gt;Kirkwood CK (1999). "Management of insomnia". &lt;i&gt;J Am Pharm Assoc&lt;/i&gt; &lt;b&gt;39&lt;/b&gt; (5): 688–96; quiz 713–4. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/10533351"&gt;PMID 10533351&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Management+of+insomnia&amp;amp;rft.jtitle=J+Am+Pharm+Assoc&amp;amp;rft.aulast=Kirkwood+CK&amp;amp;rft.au=Kirkwood+CK&amp;amp;rft.date=1999&amp;amp;rft.volume=39&amp;amp;rft.issue=5&amp;amp;rft.pages=688%E2%80%9396%3B+quiz+713%E2%80%934&amp;amp;rft_id=info:pmid/10533351&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-JacobsG2004Cognitive-17"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFJacobsEdward_F._Pace-Schott.2C_Robert_Stickgold.2C_Michael_W._Otto2004"&gt;Jacobs, Gregg; Edward F. Pace-Schott, Robert Stickgold, Michael W. Otto (September 27, 2004). "&lt;a class="external text" title="http://archinte.ama-assn.org/cgi/content/full/164/17/1888?ijkey=6a2af558a671b089d7c77db5fc5f53a450fd1cda" rel="nofollow"&gt;Cognitive Behavior Therapy and Pharmacotherapy for Insomnia: A Randomized Controlled Trial and Direct Comparison&lt;/a&gt;". &lt;i&gt;&lt;a title="Archives of Internal Medicine"&gt;Archives of Internal Medicine&lt;/a&gt;&lt;/i&gt; &lt;b&gt;164&lt;/b&gt; (17): 1888–1896. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1001%2Farchinte.164.17.1888" rel="nofollow"&gt;10.1001/archinte.164.17.1888&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/15451764"&gt;PMID 15451764&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://archinte.ama-assn.org/cgi/content/full/164/17/1888?ijkey=6a2af558a671b089d7c77db5fc5f53a450fd1cda" rel="nofollow"&gt;http://archinte.ama-assn.org/cgi/content/full/164/17/1888?ijkey=6a2af558a671b089d7c77db5fc5f53a450fd1cda&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Cognitive+Behavior+Therapy+and+Pharmacotherapy+for+Insomnia%3A+A+Randomized+Controlled+Trial+and+Direct+Comparison&amp;amp;rft.jtitle=%5B%5BArchives+of+Internal+Medicine%5D%5D&amp;amp;rft.aulast=Jacobs&amp;amp;rft.aufirst=Gregg&amp;amp;rft.au=Jacobs%2C+Gregg&amp;amp;rft.au=Edward+F.+Pace-Schott%2C+Robert+Stickgold%2C+Michael+W.+Otto&amp;amp;rft.date=September+27%2C+2004&amp;amp;rft.volume=164&amp;amp;rft.issue=17&amp;amp;rft.pages=1888%E2%80%931896&amp;amp;rft_id=info:doi/10.1001%2Farchinte.164.17.1888&amp;amp;rft_id=info:pmid/15451764&amp;amp;rft_id=http%3A%2F%2Farchinte.ama-assn.org%2Fcgi%2Fcontent%2Ffull%2F164%2F17%2F1888%3Fijkey%3D6a2af558a671b089d7c77db5fc5f53a450fd1cda&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-18"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFMorin.2C_C._M.1999"&gt;Morin, C. M. (1999). "&lt;a class="external text" title="http://jama.ama-assn.org/cgi/content/full/281/11/991" rel="nofollow"&gt;Behavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial&lt;/a&gt;". &lt;i&gt;JAMA the Journal of the American Medical Association&lt;/i&gt; &lt;b&gt;281&lt;/b&gt;: 991. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1001%2Fjama.281.11.991" rel="nofollow"&gt;10.1001/jama.281.11.991&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/10086433"&gt;PMID 10086433&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://jama.ama-assn.org/cgi/content/full/281/11/991" rel="nofollow"&gt;http://jama.ama-assn.org/cgi/content/full/281/11/991&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Behavioral+and+Pharmacological+Therapies+for+Late-Life+Insomnia%3A+A+Randomized+Controlled+Trial&amp;amp;rft.jtitle=JAMA+the+Journal+of+the+American+Medical+Association&amp;amp;rft.aulast=Morin%2C+C.+M.&amp;amp;rft.au=Morin%2C+C.+M.&amp;amp;rft.date=1999&amp;amp;rft.volume=281&amp;amp;rft.pages=991&amp;amp;rft_id=info:doi/10.1001%2Fjama.281.11.991&amp;amp;rft_id=info:pmid/10086433&amp;amp;rft_id=http%3A%2F%2Fjama.ama-assn.org%2Fcgi%2Fcontent%2Ffull%2F281%2F11%2F991&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-19"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFKARL_E._MILLER.2C_M.D.2005"&gt;KARL E. MILLER, M.D. (July 2005). "&lt;a class="external text" title="http://www.aafp.org/afp/20050715/tips/7.html" rel="nofollow"&gt;Cognitive Behavior Therapy vs. Pharmacotherapy for Insomnia&lt;/a&gt;". &lt;i&gt;American Family Physician&lt;/i&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.aafp.org/afp/20050715/tips/7.html" rel="nofollow"&gt;http://www.aafp.org/afp/20050715/tips/7.html&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Cognitive+Behavior+Therapy+vs.+Pharmacotherapy+for+Insomnia&amp;amp;rft.jtitle=American+Family+Physician&amp;amp;rft.aulast=KARL+E.+MILLER%2C+M.D.&amp;amp;rft.au=KARL+E.+MILLER%2C+M.D.&amp;amp;rft.date=July+2005&amp;amp;rft_id=http%3A%2F%2Fwww.aafp.org%2Fafp%2F20050715%2Ftips%2F7.html&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-20"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFGlass_J.2C_Lanct.C3.B4t_KL.2C_Herrmann_N.2C_Sproule_BA.2C_Busto_UE2005"&gt;Glass J, Lanctôt KL, Herrmann N, Sproule BA, Busto UE (November 2005). "&lt;a class="external text" title="http://www.bmj.com/cgi/content/full/331/7526/1169" rel="nofollow"&gt;Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits&lt;/a&gt;". &lt;i&gt;BMJ&lt;/i&gt; &lt;b&gt;331&lt;/b&gt; (7526): 1169. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1136%2Fbmj.38623.768588.47" rel="nofollow"&gt;10.1136/bmj.38623.768588.47&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/16284208"&gt;PMID 16284208&lt;/a&gt;. &lt;a title="PubMed Central"&gt;PMC&lt;/a&gt;: &lt;a class="external text" title="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&amp;amp;artid=1285093" rel="nofollow"&gt;1285093&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.bmj.com/cgi/content/full/331/7526/1169" rel="nofollow"&gt;http://www.bmj.com/cgi/content/full/331/7526/1169&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Sedative+hypnotics+in+older+people+with+insomnia%3A+meta-analysis+of+risks+and+benefits&amp;amp;rft.jtitle=BMJ&amp;amp;rft.aulast=Glass+J%2C+Lanct%C3%B4t+KL%2C+Herrmann+N%2C+Sproule+BA%2C+Busto+UE&amp;amp;rft.au=Glass+J%2C+Lanct%C3%B4t+KL%2C+Herrmann+N%2C+Sproule+BA%2C+Busto+UE&amp;amp;rft.date=November+2005&amp;amp;rft.volume=331&amp;amp;rft.issue=7526&amp;amp;rft.pages=1169&amp;amp;rft_id=info:doi/10.1136%2Fbmj.38623.768588.47&amp;amp;rft_id=info:pmid/16284208&amp;amp;rft_id=http%3A%2F%2Fwww.bmj.com%2Fcgi%2Fcontent%2Ffull%2F331%2F7526%2F1169&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid17619935-21"&gt;^ &lt;sup&gt;&lt;i&gt;&lt;b&gt;a&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;sup&gt;&lt;i&gt;&lt;b&gt;b&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;sup&gt;&lt;i&gt;&lt;b&gt;c&lt;/b&gt;&lt;/i&gt;&lt;/sup&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFBuscemi_N.2C_Vandermeer_B.2C_Friesen_C.2C_Bialy_L.2C_Tubman_M.2C_Ospina_M.2C_Klassen_TP.2C_Witmans_M.2007"&gt;Buscemi N, Vandermeer B, Friesen C, Bialy L, Tubman M, Ospina M, Klassen TP, Witmans M. (September 2007). "The efficacy and safety of drug treatments for chronic insomnia in adults: a meta-analysis of RCTs". &lt;i&gt;J Gen Intern Med&lt;/i&gt; &lt;b&gt;22&lt;/b&gt; (9): 1335–1350. &lt;/cite&gt;&lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1007%2Fs11606-007-0251-z" rel="nofollow"&gt;10.1007/s11606-007-0251-z&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/17619935"&gt;PMID 17619935&lt;/a&gt;.&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=The+efficacy+and+safety+of+drug+treatments+for+chronic+insomnia+in+adults%3A+a+meta-analysis+of+RCTs&amp;amp;rft.jtitle=J+Gen+Intern+Med&amp;amp;rft.aulast=Buscemi+N%2C+Vandermeer+B%2C+Friesen+C%2C+Bialy+L%2C+Tubman+M%2C+Ospina+M%2C+Klassen+TP%2C+Witmans+M.&amp;amp;rft.au=Buscemi+N%2C+Vandermeer+B%2C+Friesen+C%2C+Bialy+L%2C+Tubman+M%2C+Ospina+M%2C+Klassen+TP%2C+Witmans+M.&amp;amp;rft.date=September+2007&amp;amp;rft.volume=22&amp;amp;rft.issue=9&amp;amp;rft.pages=1335%26ndash%3B1350&amp;amp;rft_id=info:doi/10.1007%2Fs11606-007-0251-z&amp;amp;rft_id=info:pmid/17619935&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-22"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFOhayon_MM.2C_Caulet_M1995"&gt;Ohayon MM, Caulet M (May 1995). "&lt;a class="external text" title="http://linkinghub.elsevier.com/retrieve/pii/027858469400023B" rel="nofollow"&gt;Insomnia and psychotropic drug consumption&lt;/a&gt;". &lt;i&gt;Prog. Neuropsychopharmacol. Biol. Psychiatry&lt;/i&gt; &lt;b&gt;19&lt;/b&gt; (3): 421–31. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1016%2F0278-5846%2894%2900023-B" rel="nofollow"&gt;10.1016/0278-5846(94)00023-B&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/7624493"&gt;PMID 7624493&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://linkinghub.elsevier.com/retrieve/pii/027858469400023B" rel="nofollow"&gt;http://linkinghub.elsevier.com/retrieve/pii/027858469400023B&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Insomnia+and+psychotropic+drug+consumption&amp;amp;rft.jtitle=Prog.+Neuropsychopharmacol.+Biol.+Psychiatry&amp;amp;rft.aulast=Ohayon+MM%2C+Caulet+M&amp;amp;rft.au=Ohayon+MM%2C+Caulet+M&amp;amp;rft.date=May+1995&amp;amp;rft.volume=19&amp;amp;rft.issue=3&amp;amp;rft.pages=421%E2%80%9331&amp;amp;rft_id=info:doi/10.1016%2F0278-5846%2894%2900023-B&amp;amp;rft_id=info:pmid/7624493&amp;amp;rft_id=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2F027858469400023B&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-23"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class=""&gt;"&lt;a class="external text" title="http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Drug-Class-Focused-Reviews/498264/" rel="nofollow"&gt;What's wrong with prescribing hypnotics?&lt;/a&gt;". &lt;i&gt;Drug Ther Bull&lt;/i&gt; &lt;b&gt;42&lt;/b&gt; (12): 89–93. December 2004. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1136%2Fdtb.2004.421289" rel="nofollow"&gt;10.1136/dtb.2004.421289&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/15587763"&gt;PMID 15587763&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Drug-Class-Focused-Reviews/498264/" rel="nofollow"&gt;http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Drug-Class-Focused-Reviews/498264/&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=What%27s+wrong+with+prescribing+hypnotics%3F&amp;amp;rft.jtitle=Drug+Ther+Bull&amp;amp;rft.date=December+2004&amp;amp;rft.volume=42&amp;amp;rft.issue=12&amp;amp;rft.pages=89%E2%80%9393&amp;amp;rft_id=info:doi/10.1136%2Fdtb.2004.421289&amp;amp;rft_id=info:pmid/15587763&amp;amp;rft_id=http%3A%2F%2Fwww.nelm.nhs.uk%2Fen%2FNeLM-Area%2FEvidence%2FDrug-Class-Focused-Reviews%2F498264%2F&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-24"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFTsoi.2C_Wf1991"&gt;Tsoi, Wf (Mar 1991). "Insomnia: drug treatment.". &lt;i&gt;Annals of the Academy of Medicine, Singapore&lt;/i&gt; &lt;b&gt;20&lt;/b&gt; (2): 269–72. &lt;a title="International Standard Serial Number"&gt;ISSN&lt;/a&gt; &lt;a class="external text" title="http://worldcat.org/issn/0304-4602" rel="nofollow"&gt;0304-4602&lt;/a&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/1679317"&gt;PMID 1679317&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Insomnia%3A+drug+treatment.&amp;amp;rft.jtitle=Annals+of+the+Academy+of+Medicine%2C+Singapore&amp;amp;rft.aulast=Tsoi%2C+Wf&amp;amp;rft.au=Tsoi%2C+Wf&amp;amp;rft.date=Mar+1991&amp;amp;rft.volume=20&amp;amp;rft.issue=2&amp;amp;rft.pages=269%E2%80%9372&amp;amp;rft_id=info:pmid/1679317&amp;amp;rft.issn=0304-4602&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-25"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFMontplaisir_J2000"&gt;Montplaisir J (August 2000). "&lt;a class="external text" title="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;amp;pubmedid=10976252" rel="nofollow"&gt;Treatment of primary insomnia&lt;/a&gt;" (PDF). &lt;i&gt;CMAJ&lt;/i&gt; &lt;b&gt;163&lt;/b&gt; (4): 389–91. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/10976252"&gt;PMID 10976252&lt;/a&gt;. &lt;a title="PubMed Central"&gt;PMC&lt;/a&gt;: &lt;a class="external text" title="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&amp;amp;artid=80369" rel="nofollow"&gt;80369&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;amp;pubmedid=10976252" rel="nofollow"&gt;http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;amp;pubmedid=10976252&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Treatment+of+primary+insomnia&amp;amp;rft.jtitle=CMAJ&amp;amp;rft.aulast=Montplaisir+J&amp;amp;rft.au=Montplaisir+J&amp;amp;rft.date=August+2000&amp;amp;rft.volume=163&amp;amp;rft.issue=4&amp;amp;rft.pages=389%E2%80%9391&amp;amp;rft_id=info:pmid/10976252&amp;amp;rft_id=http%3A%2F%2Fwww.pubmedcentral.nih.gov%2Farticlerender.fcgi%3Ftool%3Dpubmed%26pubmedid%3D10976252&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-26"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web" id="CITEREFWHO2006"&gt;&lt;a title="World Health Organisation" class="mw-redirect"&gt;WHO&lt;/a&gt; (2006). &lt;a class="external text" title="http://www.who.int/medicines/areas/quality_safety/4.6ZopicloneCritReview.pdf" rel="nofollow"&gt;"World Health Organisation - Assessment of Zopiclone"&lt;/a&gt; (PDF). who.int&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.who.int/medicines/areas/quality_safety/4.6ZopicloneCritReview.pdf" rel="nofollow"&gt;http://www.who.int/medicines/areas/quality_safety/4.6ZopicloneCritReview.pdf&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=World+Health+Organisation+-+Assessment+of+Zopiclone&amp;amp;rft.atitle=&amp;amp;rft.aulast=WHO&amp;amp;rft.au=WHO&amp;amp;rft.date=2006&amp;amp;rft.pub=who.int&amp;amp;rft_id=http%3A%2F%2Fwww.who.int%2Fmedicines%2Fareas%2Fquality_safety%2F4.6ZopicloneCritReview.pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-27"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFRowlett_JK.2C_Woolverton_WL1996"&gt;Rowlett JK, Woolverton WL (November 1996). "&lt;a class="external text" title="http://www.springerlink.com/content/xeu44evyanvw1n65/fulltext.pdf" rel="nofollow"&gt;Assessment of benzodiazepine receptor heterogeneity in vivo: apparent pA2 and pKB analyses from behavioral studies&lt;/a&gt;". &lt;i&gt;Psychopharmacology (Berl.)&lt;/i&gt; &lt;b&gt;128&lt;/b&gt; (1): 1–16. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1007%2Fs002130050103" rel="nofollow"&gt;10.1007/s002130050103&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/8944400"&gt;PMID 8944400&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.springerlink.com/content/xeu44evyanvw1n65/fulltext.pdf" rel="nofollow"&gt;http://www.springerlink.com/content/xeu44evyanvw1n65/fulltext.pdf&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Assessment+of+benzodiazepine+receptor+heterogeneity+in+vivo%3A+apparent+pA2+and+pKB+analyses+from+behavioral+studies&amp;amp;rft.jtitle=Psychopharmacology+%28Berl.%29&amp;amp;rft.aulast=Rowlett+JK%2C+Woolverton+WL&amp;amp;rft.au=Rowlett+JK%2C+Woolverton+WL&amp;amp;rft.date=November+1996&amp;amp;rft.volume=128&amp;amp;rft.issue=1&amp;amp;rft.pages=1%E2%80%9316&amp;amp;rft_id=info:doi/10.1007%2Fs002130050103&amp;amp;rft_id=info:pmid/8944400&amp;amp;rft_id=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxeu44evyanvw1n65%2Ffulltext.pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-28"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFNoguchi_HKitazumi_K.2C_Mori_M.2C_Shiba_T.2004"&gt;Noguchi H; Kitazumi K, Mori M, Shiba T. (March 2004). "&lt;a class="external text" title="http://www.jstage.jst.go.jp/article/jphs/94/3/246/_pdf" rel="nofollow"&gt;Electroencephalographic properties of zaleplon, a non-benzodiazepine sedative/hypnotic, in rats&lt;/a&gt;" (pdf). &lt;i&gt;J Pharmacol Sci.&lt;/i&gt; &lt;b&gt;94&lt;/b&gt; (3): 246–51. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1254%2Fjphs.94.246" rel="nofollow"&gt;10.1254/jphs.94.246&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/15037809"&gt;PMID 15037809&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.jstage.jst.go.jp/article/jphs/94/3/246/_pdf" rel="nofollow"&gt;http://www.jstage.jst.go.jp/article/jphs/94/3/246/_pdf&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Electroencephalographic+properties+of+zaleplon%2C+a+non-benzodiazepine+sedative%2Fhypnotic%2C+in+rats&amp;amp;rft.jtitle=J+Pharmacol+Sci.&amp;amp;rft.aulast=Noguchi+H&amp;amp;rft.au=Noguchi+H&amp;amp;rft.au=Kitazumi+K%2C+Mori+M%2C+Shiba+T.&amp;amp;rft.date=March+2004&amp;amp;rft.volume=94&amp;amp;rft.issue=3&amp;amp;rft.pages=246%E2%80%9351&amp;amp;rft_id=info:doi/10.1254%2Fjphs.94.246&amp;amp;rft_id=info:pmid/15037809&amp;amp;rft_id=http%3A%2F%2Fwww.jstage.jst.go.jp%2Farticle%2Fjphs%2F94%2F3%2F246%2F_pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-29"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFBertschy_G.2C_Ragama-Pardos_E.2C_Muscionico_M.2C_.27.27et_al.27.272005"&gt;Bertschy G, Ragama-Pardos E, Muscionico M, &lt;i&gt;et al&lt;/i&gt; (January 2005). "Trazodone addition for insomnia in venlafaxine-treated, depressed inpatients: a semi-naturalistic study". &lt;i&gt;Pharmacol. Res.&lt;/i&gt; &lt;b&gt;51&lt;/b&gt; (1): 79–84. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1016%2Fj.phrs.2004.06.007" rel="nofollow"&gt;10.1016/j.phrs.2004.06.007&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/15519538"&gt;PMID 15519538&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Trazodone+addition+for+insomnia+in+venlafaxine-treated%2C+depressed+inpatients%3A+a+semi-naturalistic+study&amp;amp;rft.jtitle=Pharmacol.+Res.&amp;amp;rft.aulast=Bertschy+G%2C+Ragama-Pardos+E%2C+Muscionico+M%2C+%27%27et+al%27%27&amp;amp;rft.au=Bertschy+G%2C+Ragama-Pardos+E%2C+Muscionico+M%2C+%27%27et+al%27%27&amp;amp;rft.date=January+2005&amp;amp;rft.volume=51&amp;amp;rft.issue=1&amp;amp;rft.pages=79%E2%80%9384&amp;amp;rft_id=info:doi/10.1016%2Fj.phrs.2004.06.007&amp;amp;rft_id=info:pmid/15519538&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-30"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFWinokur_A.2C_DeMartinis_NA_3rd.2C_McNally_DP.2C_Gary_EM.2C_Cormier_JL.2C_Gary_KA._.2C_.27.27et_al.27.27"&gt;Winokur A, DeMartinis NA 3rd, McNally DP, Gary EM, Cormier JL, Gary KA. , &lt;i&gt;et al&lt;/i&gt; (August url=&lt;a class="external free" title="http://www.ncbi.nlm.nih.gov/pubmed/14658972?ordinalpos=30&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum).&amp;amp;#32" rel="nofollow"&gt;http://www.ncbi.nlm.nih.gov/pubmed/14658972?ordinalpos=30&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum).&amp;amp;#32&lt;/a&gt;;"Comparative effects of mirtazapine and fluoxetine on sleep physiology measures in patients with major depression and insomnia". &lt;i&gt;J Clin Psychiatry year=2003&lt;/i&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Comparative+effects+of+mirtazapine+and+fluoxetine+on+sleep+physiology+measures+in+patients+with+major+depression+and+insomnia&amp;amp;rft.jtitle=J+Clin+Psychiatry+year%3D2003&amp;amp;rft.aulast=Winokur+A%2C+DeMartinis+NA+3rd%2C+McNally+DP%2C+Gary+EM%2C+Cormier+JL%2C+Gary+KA.+%2C+%27%27et+al%27%27&amp;amp;rft.au=Winokur+A%2C+DeMartinis+NA+3rd%2C+McNally+DP%2C+Gary+EM%2C+Cormier+JL%2C+Gary+KA.+%2C+%27%27et+al%27%27&amp;amp;rft.date=August+url%3Dhttp%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F14658972%3Fordinalpos%3D30%26itool%3DEntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-31"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFSchittecatte_M.2C_Dumont_F.2C_Machowski_R.2C_Cornil_C.2C_Lavergne_F.2C_Wilmotte_J_.2C_.27.27et_al.27.27"&gt;Schittecatte M, Dumont F, Machowski R, Cornil C, Lavergne F, Wilmotte J , &lt;i&gt;et al&lt;/i&gt;. "Effects of mirtazapine on sleep polygraphic variables in major depression". &lt;i&gt;Neuropsychobiology year=2002 url=&lt;a class="external free" title="http://www.ncbi.nlm.nih.gov/pubmed/12566938?ordinalpos=62&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum" rel="nofollow"&gt;http://www.ncbi.nlm.nih.gov/pubmed/12566938?ordinalpos=62&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum&lt;/a&gt;&lt;/i&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Effects+of+mirtazapine+on+sleep+polygraphic+variables+in+major+depression&amp;amp;rft.jtitle=Neuropsychobiology+year%3D2002++url%3Dhttp%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F12566938%3Fordinalpos%3D62%26itool%3DEntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum&amp;amp;rft.aulast=Schittecatte+M%2C+Dumont+F%2C+Machowski+R%2C+Cornil+C%2C+Lavergne+F%2C+Wilmotte+J+%2C+%27%27et+al%27%27&amp;amp;rft.au=Schittecatte+M%2C+Dumont+F%2C+Machowski+R%2C+Cornil+C%2C+Lavergne+F%2C+Wilmotte+J+%2C+%27%27et+al%27%27&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-32"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFPaul_MA.2C_Gray_G.2C_Sardana_TM.2C_Pigeau_RA2004"&gt;Paul MA, Gray G, Sardana TM, Pigeau RA (May 2004). "Melatonin and zopiclone as facilitators of early circadian sleep in operational air transport crews". &lt;i&gt;Aviat Space Environ Med&lt;/i&gt; &lt;b&gt;75&lt;/b&gt; (5): 439–43. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/15152897"&gt;PMID 15152897&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Melatonin+and+zopiclone+as+facilitators+of+early+circadian+sleep+in+operational+air+transport+crews&amp;amp;rft.jtitle=Aviat+Space+Environ+Med&amp;amp;rft.aulast=Paul+MA%2C+Gray+G%2C+Sardana+TM%2C+Pigeau+RA&amp;amp;rft.au=Paul+MA%2C+Gray+G%2C+Sardana+TM%2C+Pigeau+RA&amp;amp;rft.date=May+2004&amp;amp;rft.volume=75&amp;amp;rft.issue=5&amp;amp;rft.pages=439%E2%80%9343&amp;amp;rft_id=info:pmid/15152897&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-33"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFPaul_MA.2C_Gray_G.2C_Kenny_G.2C_Pigeau_RA2003"&gt;Paul MA, Gray G, Kenny G, Pigeau RA (December 2003). "Impact of melatonin, zaleplon, zopiclone, and temazepam on psychomotor performance". &lt;i&gt;Aviat Space Environ Med&lt;/i&gt; &lt;b&gt;74&lt;/b&gt; (12): 1263–70. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/14692469"&gt;PMID 14692469&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Impact+of+melatonin%2C+zaleplon%2C+zopiclone%2C+and+temazepam+on+psychomotor+performance&amp;amp;rft.jtitle=Aviat+Space+Environ+Med&amp;amp;rft.aulast=Paul+MA%2C+Gray+G%2C+Kenny+G%2C+Pigeau+RA&amp;amp;rft.au=Paul+MA%2C+Gray+G%2C+Kenny+G%2C+Pigeau+RA&amp;amp;rft.date=December+2003&amp;amp;rft.volume=74&amp;amp;rft.issue=12&amp;amp;rft.pages=1263%E2%80%9370&amp;amp;rft_id=info:pmid/14692469&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-34"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFZhdanova_IV.2C_Tucci_V2003"&gt;Zhdanova IV, Tucci V (May 2003). "&lt;a class="external text" title="http://www.treatment-options.com/1092-8480/5/225" rel="nofollow"&gt;Melatonin, Circadian Rhythms, and Sleep&lt;/a&gt;" (&lt;sup class="noprint Inline-Template"&gt;&lt;span title=" since April 2009" style="white-space: nowrap;"&gt;[&lt;i&gt;&lt;a title="Wikipedia:Dead external links"&gt;dead link&lt;/a&gt;&lt;/i&gt;]&lt;/span&gt;&lt;/sup&gt; – &lt;sup&gt;&lt;a class="external text" title="http://scholar.google.co.uk/scholar?hl=en&amp;amp;lr=&amp;amp;q=intitle%3AMelatonin%2C+Circadian+Rhythms%2C+and+Sleep&amp;amp;as_publication=Curr+Treat+Options+Neurol&amp;amp;as_ylo=2003&amp;amp;as_yhi=2003&amp;amp;btnG=Search" rel="nofollow"&gt;Scholar search&lt;/a&gt;&lt;/sup&gt;). &lt;i&gt;Curr Treat Options Neurol&lt;/i&gt; &lt;b&gt;5&lt;/b&gt; (3): 225–229. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1007%2Fs11940-003-0013-0" rel="nofollow"&gt;10.1007/s11940-003-0013-0&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/12670411"&gt;PMID 12670411&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.treatment-options.com/1092-8480/5/225" rel="nofollow"&gt;http://www.treatment-options.com/1092-8480/5/225&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Melatonin%2C+Circadian+Rhythms%2C+and+Sleep&amp;amp;rft.jtitle=Curr+Treat+Options+Neurol&amp;amp;rft.aulast=Zhdanova+IV%2C+Tucci+V&amp;amp;rft.au=Zhdanova+IV%2C+Tucci+V&amp;amp;rft.date=May+2003&amp;amp;rft.volume=5&amp;amp;rft.issue=3&amp;amp;rft.pages=225%E2%80%93229&amp;amp;rft_id=info:doi/10.1007%2Fs11940-003-0013-0&amp;amp;rft_id=info:pmid/12670411&amp;amp;rft_id=http%3A%2F%2Fwww.treatment-options.com%2F1092-8480%2F5%2F225&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-35"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFRajaratnamPolymeropoulos_MH.2C_Fisher_DM.2C_Roth_T.2C_Scott_C.2C_Birznieks_G.2C_Klerman_EB2008"&gt;Rajaratnam, SMW; Polymeropoulos MH, Fisher DM, Roth T, Scott C, Birznieks G, Klerman EB (2 December 2008). "Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials". &lt;i&gt;Lancet&lt;/i&gt; &lt;b&gt;373&lt;/b&gt;: 482. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1016%2FS0140-6736%2808%2961812-7" rel="nofollow"&gt;10.1016/S0140-6736(08)61812-7&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Melatonin+agonist+tasimelteon+%28VEC-162%29+for+transient+insomnia+after+sleep-time+shift%3A+two+randomised+controlled+multicentre+trials&amp;amp;rft.jtitle=Lancet&amp;amp;rft.aulast=Rajaratnam&amp;amp;rft.aufirst=SMW&amp;amp;rft.au=Rajaratnam%2C+SMW&amp;amp;rft.au=Polymeropoulos+MH%2C+Fisher+DM%2C+Roth+T%2C+Scott+C%2C+Birznieks+G%2C+Klerman+EB&amp;amp;rft.date=2+December+2008&amp;amp;rft.volume=373&amp;amp;rft.pages=482&amp;amp;rft_id=info:doi/10.1016%2FS0140-6736%2808%2961812-7&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid17803013-36"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFZammit_G.2C_Erman_M.2C_Wang-Weigand_S.2C_Sainati_S.2C_Zhang_J.2C_Roth_T2007"&gt;Zammit G, Erman M, Wang-Weigand S, Sainati S, Zhang J, Roth T (August 2007). "&lt;a class="external text" title="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&amp;amp;artid=1978328" rel="nofollow"&gt;Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia&lt;/a&gt;". &lt;i&gt;J Clin Sleep Med&lt;/i&gt; &lt;b&gt;3&lt;/b&gt; (5): 495–504. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/17803013"&gt;PMID 17803013&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Evaluation+of+the+efficacy+and+safety+of+ramelteon+in+subjects+with+chronic+insomnia&amp;amp;rft.jtitle=J+Clin+Sleep+Med&amp;amp;rft.aulast=Zammit+G%2C+Erman+M%2C+Wang-Weigand+S%2C+Sainati+S%2C+Zhang+J%2C+Roth+T&amp;amp;rft.au=Zammit+G%2C+Erman+M%2C+Wang-Weigand+S%2C+Sainati+S%2C+Zhang+J%2C+Roth+T&amp;amp;rft.date=August+2007&amp;amp;rft.volume=3&amp;amp;rft.issue=5&amp;amp;rft.pages=495%E2%80%93504&amp;amp;rft_id=info:pmid/17803013&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-37"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; Morton Walker, DPM - &lt;span class="external text"&gt;The Restoration of L-Tryptophan with Its Numerous Physiological Benefits&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-38"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFTokunaga_STakeda_Y.2C_Shinomiya_K.2C_Hirase_M.2C_Kamei_C.2007"&gt;Tokunaga S; Takeda Y, Shinomiya K, Hirase M, Kamei C. (February 2007). "&lt;a class="external text" title="http://www.jstage.jst.go.jp/article/jphs/103/2/201/_pdf" rel="nofollow"&gt;Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats&lt;/a&gt;" (pdf). &lt;i&gt;J Pharmacol Sci.&lt;/i&gt; &lt;b&gt;103&lt;/b&gt; (2): 201–6. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1254%2Fjphs.FP0061173" rel="nofollow"&gt;10.1254/jphs.FP0061173&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/17287588"&gt;PMID 17287588&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.jstage.jst.go.jp/article/jphs/103/2/201/_pdf" rel="nofollow"&gt;http://www.jstage.jst.go.jp/article/jphs/103/2/201/_pdf&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Effects+of+some+H1-antagonists+on+the+sleep-wake+cycle+in+sleep-disturbed+rats&amp;amp;rft.jtitle=J+Pharmacol+Sci.&amp;amp;rft.aulast=Tokunaga+S&amp;amp;rft.au=Tokunaga+S&amp;amp;rft.au=Takeda+Y%2C+Shinomiya+K%2C+Hirase+M%2C+Kamei+C.&amp;amp;rft.date=February+2007&amp;amp;rft.volume=103&amp;amp;rft.issue=2&amp;amp;rft.pages=201%E2%80%936&amp;amp;rft_id=info:doi/10.1254%2Fjphs.FP0061173&amp;amp;rft_id=info:pmid/17287588&amp;amp;rft_id=http%3A%2F%2Fwww.jstage.jst.go.jp%2Farticle%2Fjphs%2F103%2F2%2F201%2F_pdf&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid10761819-39"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFDonath_F.2C_Quispe_S.2C_Diefenbach_K.2C_Maurer_A.2C_Fietze_I.2C_Roots_I2000"&gt;Donath F, Quispe S, Diefenbach K, Maurer A, Fietze I, Roots I (2000). "Critical evaluation of the effect of valerian extract on sleep structure and sleep quality". &lt;i&gt;Pharmacopsychiatry&lt;/i&gt; &lt;b&gt;33&lt;/b&gt; (2): 47–53. &lt;a title="Digital object identifier"&gt;doi&lt;/a&gt;:&lt;span class="neverexpand"&gt;&lt;a class="external text" title="http://dx.doi.org/10.1055%2Fs-2000-7972" rel="nofollow"&gt;10.1055/s-2000-7972&lt;/a&gt;&lt;/span&gt;. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/10761819"&gt;PMID 10761819&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Critical+evaluation+of+the+effect+of+valerian+extract+on+sleep+structure+and+sleep+quality&amp;amp;rft.jtitle=Pharmacopsychiatry&amp;amp;rft.aulast=Donath+F%2C+Quispe+S%2C+Diefenbach+K%2C+Maurer+A%2C+Fietze+I%2C+Roots+I&amp;amp;rft.au=Donath+F%2C+Quispe+S%2C+Diefenbach+K%2C+Maurer+A%2C+Fietze+I%2C+Roots+I&amp;amp;rft.date=2000&amp;amp;rft.volume=33&amp;amp;rft.issue=2&amp;amp;rft.pages=47%E2%80%9353&amp;amp;rft_id=info:doi/10.1055%2Fs-2000-7972&amp;amp;rft_id=info:pmid/10761819&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid16335333-40"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFMorin_CM.2C_Koetter_U.2C_Bastien_C.2C_Ware_JC.2C_Wooten_V2005"&gt;Morin CM, Koetter U, Bastien C, Ware JC, Wooten V (2005). "Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial". &lt;i&gt;Sleep&lt;/i&gt; &lt;b&gt;28&lt;/b&gt; (11): 1465–71. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/16335333"&gt;PMID 16335333&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Valerian-hops+combination+and+diphenhydramine+for+treating+insomnia%3A+a+randomized+placebo-controlled+clinical+trial&amp;amp;rft.jtitle=Sleep&amp;amp;rft.aulast=Morin+CM%2C+Koetter+U%2C+Bastien+C%2C+Ware+JC%2C+Wooten+V&amp;amp;rft.au=Morin+CM%2C+Koetter+U%2C+Bastien+C%2C+Ware+JC%2C+Wooten+V&amp;amp;rft.date=2005&amp;amp;rft.volume=28&amp;amp;rft.issue=11&amp;amp;rft.pages=1465%E2%80%9371&amp;amp;rft_id=info:pmid/16335333&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid17561634-41"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFMeolie_AL.2C_Rosen_C.2C_Kristo_D.2C_.27.27et_al.27.272005"&gt;Meolie AL, Rosen C, Kristo D, &lt;i&gt;et al&lt;/i&gt; (2005). "Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence". &lt;i&gt;Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine&lt;/i&gt; &lt;b&gt;1&lt;/b&gt; (2): 173–87. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/17561634"&gt;PMID 17561634&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Oral+nonprescription+treatment+for+insomnia%3A+an+evaluation+of+products+with+limited+evidence&amp;amp;rft.jtitle=Journal+of+clinical+sleep+medicine+%3A+JCSM+%3A+official+publication+of+the+American+Academy+of+Sleep+Medicine&amp;amp;rft.aulast=Meolie+AL%2C+Rosen+C%2C+Kristo+D%2C+%27%27et+al%27%27&amp;amp;rft.au=Meolie+AL%2C+Rosen+C%2C+Kristo+D%2C+%27%27et+al%27%27&amp;amp;rft.date=2005&amp;amp;rft.volume=1&amp;amp;rft.issue=2&amp;amp;rft.pages=173%E2%80%9387&amp;amp;rft_id=info:pmid/17561634&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-42"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;span class="external text"&gt;http://www.cannabis.net/medical-marijuana/pot-docs.html&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-pmid9703590-43"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="" id="CITEREFHornyak_M.2C_Voderholzer_U.2C_Hohagen_F.2C_Berger_M.2C_Riemann_D1998"&gt;Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D (1998). "Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study". &lt;i&gt;Sleep&lt;/i&gt; &lt;b&gt;21&lt;/b&gt; (5): 501–5. &lt;a class="external" title="http://www.ncbi.nlm.nih.gov/pubmed/9703590"&gt;PMID 9703590&lt;/a&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.genre=article&amp;amp;rft.atitle=Magnesium+therapy+for+periodic+leg+movements-related+insomnia+and+restless+legs+syndrome%3A+an+open+pilot+study&amp;amp;rft.jtitle=Sleep&amp;amp;rft.aulast=Hornyak+M%2C+Voderholzer+U%2C+Hohagen+F%2C+Berger+M%2C+Riemann+D&amp;amp;rft.au=Hornyak+M%2C+Voderholzer+U%2C+Hohagen+F%2C+Berger+M%2C+Riemann+D&amp;amp;rft.date=1998&amp;amp;rft.volume=21&amp;amp;rft.issue=5&amp;amp;rft.pages=501%E2%80%935&amp;amp;rft_id=info:pmid/9703590&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-44"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;cite style="font-style: normal;" class="web"&gt;&lt;a class="external text" title="http://www.cidervinegar.org/2007/06/cider-vinegar-rocks.html" rel="nofollow"&gt;"Cider Vinegar and Insomnia"&lt;/a&gt;&lt;span class="printonly"&gt;. &lt;a class="external free" title="http://www.cidervinegar.org/2007/06/cider-vinegar-rocks.html" rel="nofollow"&gt;http://www.cidervinegar.org/2007/06/cider-vinegar-rocks.html&lt;/a&gt;&lt;/span&gt;.&lt;/cite&gt;&lt;span class="Z3988" title="ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;amp;rft.genre=bookitem&amp;amp;rft.btitle=Cider+Vinegar+and+Insomnia&amp;amp;rft.atitle=&amp;amp;rft_id=http%3A%2F%2Fwww.cidervinegar.org%2F2007%2F06%2Fcider-vinegar-rocks.html&amp;amp;rfr_id=info:sid/en.wikipedia.org:Insomnia"&gt;&lt;span style="display: none;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;&lt;li id="cite_note-45"&gt;&lt;b&gt;&lt;a title=""&gt;^&lt;/a&gt;&lt;/b&gt; &lt;span class="external free"&gt;http://www.naturdoctor.com/Chapters/Research/insomnia_tryptophan.html&lt;/span&gt;&lt;/li&gt;&lt;/ol&gt;Source : http://en.wikipedia.org/wiki/Insomnia&lt;a href="http://www.bosspulsa.com/"&gt;&lt;br /&gt;&lt;/a&gt;&lt;/div&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/8977896270362279183-6676960464710618577?l=insomniatherapycenter.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/6676960464710618577/comments/default' title='Poskan Komentar'/><link rel='replies' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/insomnia.html#comment-form' title='1 Komentar'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/6676960464710618577'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/6676960464710618577'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/insomnia.html' title='Insomnia'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><thr:total>1</thr:total></entry><entry><id>tag:blogger.com,1999:blog-8977896270362279183.post-4455606672956268558</id><published>2009-04-16T23:42:00.000-07:00</published><updated>2009-04-16T23:45:15.569-07:00</updated><title type='text'>What Is Insomnia?</title><content type='html'>&lt;h2 style="font-weight: normal;"&gt;&lt;span style="font-size:100%;"&gt;&lt;span style="font-size:130%;"&gt;Insomnia is a sleep disorder that is characterized by difficulty falling and/or staying asleep. People with insomnia have one or more of the following symptoms&lt;/span&gt;:&lt;/span&gt;&lt;/h2&gt;     &lt;div class="subhead_fmt"&gt;     &lt;/div&gt;               &lt;ul&gt;&lt;li&gt;Difficulty falling asleep&lt;/li&gt;&lt;li&gt;Waking up often during the night and having trouble going back to sleep&lt;/li&gt;&lt;li&gt;Waking up too early in the morning&lt;/li&gt;&lt;li&gt;Feeling tired upon waking&lt;/li&gt;&lt;/ul&gt;     &lt;h3&gt;Types of Insomnia&lt;/h3&gt;     &lt;p&gt;There are two types of insomnia: primary insomnia and secondary insomnia.&lt;/p&gt;     &lt;ul&gt;&lt;li&gt;         &lt;strong&gt;Primary insomnia:&lt;/strong&gt; Primary insomnia means that a person is having sleep problems that are not directly associated with any other health condition or problem.&lt;/li&gt;&lt;li&gt;         &lt;strong&gt;Secondary insomnia:&lt;/strong&gt; Secondary insomnia means that a person is having sleep problems because of something else, such as a health condition (like asthma, depression, arthritis, cancer, or heartburn); pain; medication they are taking; or a substance they are using (like alcohol).&lt;/li&gt;&lt;/ul&gt;     &lt;h3&gt;Acute vs. Chronic Insomnia&lt;/h3&gt;     &lt;p&gt;Insomnia also varies in how long it lasts and how often it occurs. It can be short-term (acute insomnia) or can last a long time (chronic insomnia). It can also come and go, with periods of time when a person has no sleep problems. Acute insomnia can last from one night to a few weeks. Insomnia is called chronic when a person has insomnia at least three nights a week for a month or longer.&lt;/p&gt;     &lt;h3&gt;Causes of Insomnia&lt;/h3&gt;     &lt;p&gt;Causes of acute insomnia can include:&lt;/p&gt;     &lt;ul&gt;&lt;li&gt;Significant life stress (job loss or change, death of a loved one, divorce, moving).&lt;/li&gt;&lt;li&gt;Illness.&lt;/li&gt;&lt;li&gt;Emotional or physical discomfort.&lt;/li&gt;&lt;li&gt;Environmental factors like noise, light, or extreme temperatures (hot or cold) that interfere with sleep.&lt;/li&gt;&lt;li&gt;Some medications (for example those used to treat colds, allergies, depression, high blood pressure, and asthma) may interfere with sleep.&lt;/li&gt;&lt;li&gt;Interferences in normal sleep schedule (jet lag or switching from a day to night shift, for example).&lt;/li&gt;&lt;/ul&gt;     &lt;p&gt;Causes of chronic insomnia include:&lt;/p&gt;     &lt;ul&gt;&lt;li&gt;Depression and/or anxiety.&lt;/li&gt;&lt;li&gt;Chronic stress.&lt;/li&gt;&lt;li&gt;Pain or discomfort at night.&lt;/li&gt;&lt;/ul&gt;     &lt;h3&gt;Symptoms of Insomnia &lt;/h3&gt;     &lt;p&gt;Symptoms of insomnia can include:&lt;/p&gt;     &lt;ul&gt;&lt;li&gt;Sleepiness during the day.&lt;/li&gt;&lt;li&gt;General tiredness.&lt;/li&gt;&lt;li&gt;Irritability.&lt;/li&gt;&lt;li&gt;Problems with concentration or memory.&lt;/li&gt;&lt;/ul&gt;     &lt;h3&gt;Diagnosing Insomnia&lt;/h3&gt;     &lt;p&gt;If you think you have insomnia, talk to your health care provider. An evaluation may include a physical exam, a medical history, and a sleep history. You may be asked to keep a sleep diary for a week or two, keeping track of your sleep patterns and how you feel during the day. Your health care provider may want to interview your bed partner about the quantity and quality of your sleep. In some cases, you may be referred to a sleep center for special tests.&lt;/p&gt;     &lt;h3&gt;Treatment for Insomnia &lt;/h3&gt;     &lt;p&gt;Acute insomnia may not require treatment. Mild insomnia often can be prevented or cured by practicing good sleep habits (see below). If your insomnia makes it hard for you to function during the day because you are sleepy and tired, your health care provider may prescribe sleeping pills for a limited time. Rapid onset, short-acting medications can help you avoid effects such as drowsiness the following day. Avoid using over-the-counter sleeping pills for insomnia since they may have undesired side effects and tend to lose their effectiveness over time.&lt;/p&gt;     &lt;p&gt;Treatment for chronic insomnia includes first treating any underlying conditions or health problems that are causing the insomnia. If insomnia continues, your health care provider may suggest behavioral therapy. Behavioral approaches help you to change behaviors that may worsen insomnia and to learn new behaviors to promote sleep. Techniques such as relaxation exercises, sleep restriction therapy, and reconditioning may be useful.&lt;/p&gt;&lt;h3&gt;Good Sleep Habits for Beating Insomnia&lt;/h3&gt;     &lt;p&gt;Good sleep habits, also called sleep hygiene, can help you get a good night's sleep and beat insomnia. Here are some tips:&lt;/p&gt;     &lt;ul&gt;&lt;li&gt;Try to go to sleep at the same time each night and get up at the same time each morning. Try not to take naps during the day because naps may make you less sleepy at night.&lt;/li&gt;&lt;li&gt;Avoid caffeine, nicotine, and alcohol late in the day. Caffeine and nicotine are stimulants and can keep you from falling asleep. Alcohol can cause waking in the night and interferes with sleep quality.&lt;/li&gt;&lt;li&gt;Get regular exercise. Try not to exercise close to bedtime because it may stimulate you and make it hard to fall asleep. Experts suggest not exercising for at least three to four hours before the time you go to sleep.&lt;/li&gt;&lt;li&gt;Don't eat a heavy meal late in the day. A light snack before bedtime, however, may help you sleep.&lt;/li&gt;&lt;li&gt;Make your bedroom comfortable. Be sure that it is dark, quiet, and not too warm or too cold. If light is a problem, try a sleeping mask. If noise is a problem, try earplugs, a fan, or a "white noise" machine to cover up the sounds.&lt;/li&gt;&lt;li&gt;Follow a routine to help you relax before sleep. Read a book, listen to music, or take a bath.&lt;/li&gt;&lt;li&gt;Avoid using your bed for anything other than sleep or sex.&lt;/li&gt;&lt;li&gt;If you can't fall asleep and don't feel drowsy, get up and read or do something that is not overly stimulating until you feel sleepy.&lt;/li&gt;&lt;li&gt;If you find yourself lying awake worrying about things, try making a to-do list before you go to bed. This may help you to not focus on those worries overnight.&lt;/li&gt;&lt;/ul&gt;     &lt;p class="text8"&gt;Reviewed by  &lt;a onclick="return sl(this,'','embd-lnk');" href="http://www.webmd.com/click?url=http://www.clevelandclinic.org/neuroscience/treat/sleep/" directive="friendlyurl" chronic_id="" object_type="" path="/webmd/click?url=http://www.clevelandclinic.org/neuroscience/treat/sleep/"&gt;The Sleep Medicine Center at The Cleveland Clinic.&lt;/a&gt;&lt;/p&gt;&lt;p class="text8"&gt;Source : &lt;a href="http://www.webmd.com/sleep-disorders/insomnia"&gt;http://www.webmd.com/sleep-disorders/insomnia&lt;/a&gt;&lt;br /&gt;&lt;/p&gt;&lt;p&gt;&lt;br /&gt;&lt;/p&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/8977896270362279183-4455606672956268558?l=insomniatherapycenter.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/4455606672956268558/comments/default' title='Poskan Komentar'/><link rel='replies' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/what-is-insomnia.html#comment-form' title='0 Komentar'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/4455606672956268558'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/4455606672956268558'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/what-is-insomnia.html' title='What Is Insomnia?'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><thr:total>0</thr:total></entry><entry><id>tag:blogger.com,1999:blog-8977896270362279183.post-2479563228695319302</id><published>2009-04-14T22:27:00.000-07:00</published><updated>2009-04-16T23:15:33.166-07:00</updated><title type='text'>Short Insomnia Therapy Beats Sleeping Pills</title><content type='html'>&lt;div class="subhead_fmt"&gt;4 Half-Hour CBT Sessions Work Better, Last Longer Than Ambien&lt;/div&gt;     &lt;div class="author_fmt"&gt;    By     &lt;a href="http://www.webmd.com/daniel-j-denoon" onclick="return sl(this,'','prog-lnk');"&gt;Daniel J. DeNoon&lt;/a&gt;&lt;br /&gt;WebMD Health News&lt;/div&gt;     &lt;div class="reviewedBy_fmt"&gt;     &lt;/div&gt;     &lt;div class="clearBoth_fmt"&gt;     &lt;/div&gt;          &lt;p&gt;Sept. 27, 2004 -- Need help getting to sleep? Four half-hour therapy sessions work better than sleeping pills, a new study shows.&lt;/p&gt;     &lt;p&gt;It's called cognitive behavioral therapy or CBT. CBT helps people recognize, challenge, and change unhelpful thoughts and behaviors. But can this really work better than modern sleeping pills?&lt;/p&gt;     &lt;p&gt;Yes, finds Gregg D. Jacobs, PhD, a psychologist at the sleep disorders clinic of Beth Israel Deaconess Medical Center and assistant professor of psychiatry at Harvard Medical School in Boston.&lt;/p&gt;     &lt;p&gt;"If someone has insomnia, [he or she doesn't] have to live with it. An effective treatment exists," Jacobs tells WebMD. "It is not a drug, but CBT. It works better than sleeping pills in the short term and in the long term -- and has no side effects."&lt;/p&gt;     &lt;p&gt;Jacobs and colleagues report their findings in the Sept. 27 issue of &lt;em&gt;Archives of Internal Medicine&lt;/em&gt;.&lt;/p&gt;     &lt;p&gt;CBT isn't a new treatment. It's already the mainstay of therapy for most sleep specialists, says Richard Simon Jr., MD, medical director of the Katheryn Severyns Dement sleep disorder center in Walla Walla, Wash.&lt;/p&gt;     &lt;p&gt;"My experience says this is right on the money," Simon tells WebMD. "As a sleep specialist I do it and I get very, very good results. No sleep specialist would disagree that CBT is the mainstay of therapy. This study clearly indicates robust effects." &lt;a onclick="return sl(this,'','embd-lnk');" href="http://www.webmd.com/content/pages/15/95727.htm" directive="friendlyurl" chronic_id="" object_type="" path="/webmd/content/pages/15/95727.htm"&gt;Having trouble sleeping? Take this quick quiz.&lt;/a&gt;&lt;/p&gt;     &lt;h3&gt;Head-to-Head: CBT vs. Ambien vs. Combination&lt;/h3&gt;     &lt;p&gt;What makes Jacobs so excited are the results of a study with 63 insomnia sufferers recruited via newspaper ads. The patients were randomly assigned to one of four treatments: CBT, Ambien, CBT plus Ambien, or a placebo pill.&lt;/p&gt;     &lt;p&gt;CBT consisted of four, 30-minute sessions (once weekly for three weeks, then a final session two weeks later) plus a 15-minute follow-up phone call.&lt;/p&gt;     &lt;p&gt;Why Ambien and not some other sleeping pill?&lt;/p&gt;     &lt;p&gt;"We picked Ambien because it is one of two approved newer-generation sleeping pills -- the other is Sonata -- that work selectively in brain and have reduced side effects," Jacobs says. " Ambien, from our perspective, is the best choice on the market if you have sleep onset problems, because it works as well as others without as many side effects."&lt;/p&gt;     &lt;p&gt;It may be the best sleeping pill for people who have trouble getting to sleep. But it doesn't work nearly as well as CBT, Jacobs and colleagues found. Insomnia sufferers got to sleep faster and more efficiently after CBT than after taking Ambien. In fact, nearly 60% of the CBT-treated patients got to sleep just as fast as people without insomnia do -- in 30 minutes or less. &lt;/p&gt;     &lt;p&gt;"These results are extremely impressive," Jacobs says. "When you take people who have long-standing insomnia -- who every night need more than an hour to fall asleep -- and say 60% get to normal sleep, that is outstanding data."&lt;/p&gt;&lt;p&gt;Source : &lt;a href="http://www.webmd.com/sleep-disorders/news/20040927/short-insomnia-therapy-beats-sleeping-pills"&gt;http://www.webmd.com/sleep-disorders/news/20040927/short-insomnia-therapy-beats-sleeping-pills&lt;/a&gt;&lt;br /&gt;&lt;/p&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/8977896270362279183-2479563228695319302?l=insomniatherapycenter.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://insomniatherapycenter.blogspot.com/feeds/2479563228695319302/comments/default' title='Poskan Komentar'/><link rel='replies' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/short-insomnia-therapy-beats-sleeping.html#comment-form' title='1 Komentar'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/2479563228695319302'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/8977896270362279183/posts/default/2479563228695319302'/><link rel='alternate' type='text/html' href='http://insomniatherapycenter.blogspot.com/2009/04/short-insomnia-therapy-beats-sleeping.html' title='Short Insomnia Therapy Beats Sleeping Pills'/><author><name>Rif'an Muazin Ibnu Asro Ar-Rifa'i</name><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='25' height='32' src='http://4.bp.blogspot.com/_JMt-MaiTnas/SiIYC_HURyI/AAAAAAAAAD4/MS2sboD1_hI/S220/n1485545942_538062_3419067.jpg'/></author><thr:total>1</thr:total></entry></feed>
